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Assessment of the Pharmacokinetics, Disposition, and Duration of Action of the Tumour-Targeting Peptide CEND-1

CEND-1 (iRGD) is a bifunctional cyclic peptide that can modulate the solid tumour microenvironment, enhancing the delivery and therapeutic index of co-administered anti-cancer agents. This study explored CEND-1’s pharmacokinetic (PK) properties pre-clinically and clinically, and assessed CEND-1 dist...

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Detalles Bibliográficos
Autores principales:	Järveläinen, Harri A., Schmithals, Christian, von Harten, Maike, Kakoschky, Bianca, Vogl, Thomas J., Harris, Stephen, Henson, Claire, Bullen-Clerkson, Gemma, Piiper, Albrecht
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053770/ https://www.ncbi.nlm.nih.gov/pubmed/36982773 http://dx.doi.org/10.3390/ijms24065700

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