Cargando…
Coupling Environmental Whole Mixture Toxicity Screening with Unbiased RNA-Seq Reveals Site-Specific Biological Responses in Zebrafish
Passive sampling device (PSD) extracts paired with developmental toxicity assays in Danio Rerio (zebrafish) are excellent sensors for whole mixture toxicity associated with the bioavailable non-polar organics at environmental sites. We expand this concept by incorporating RNA-Seq in 48-h post fertil...
Autores principales: | Rude, Christian I., Tidwell, Lane G., Tilton, Susan C., Waters, Katrina M., Anderson, Kim A., Tanguay, Robyn L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053777/ https://www.ncbi.nlm.nih.gov/pubmed/36976966 http://dx.doi.org/10.3390/toxics11030201 |
Ejemplares similares
-
3′ RNA-seq is superior to standard RNA-seq in cases of sparse data but inferior at identifying toxicity pathways in a model organism
por: McClure, Ryan S., et al.
Publicado: (2023) -
Coupling Genome-wide Transcriptomics and Developmental Toxicity Profiles in Zebrafish to Characterize Polycyclic Aromatic Hydrocarbon (PAH) Hazard
por: Shankar, Prarthana, et al.
Publicado: (2019) -
Gene co-expression network analysis in zebrafish reveals chemical class specific modules
por: Shankar, Prarthana, et al.
Publicado: (2021) -
Leveraging Multiple Data Streams for Prioritization of Mixtures for Hazard Characterization
por: Rivera, Brianna N., et al.
Publicado: (2022) -
Concentration-response gene expression analysis in zebrafish reveals phenotypically-anchored transcriptional responses to retene
por: Wilson, Lindsay B., et al.
Publicado: (2022)