Cargando…

Suramin Affects the Renal VEGF-A/VEGFR Axis in Short-Term Streptozotocin-Induced Diabetes

Diabetic nephropathy (DN) accounts for approximately 50% of end-stage renal diseases. Vascular endothelial growth factor A (VEGF-A) is thought to be a critical mediator of vascular dysfunction in DN, but its role is unclear. The lack of pharmacological tools to modify renal concentrations further hi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chyła-Danił, Gabriela, Sałaga-Zaleska, Kornelia, Kreft, Ewelina, Krzesińska, Aleksandra, Herman, Sylwia, Kuchta, Agnieszka, Sakowicz-Burkiewicz, Monika, Lenartowicz, Małgorzata, Jankowski, Maciej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053825/ https://www.ncbi.nlm.nih.gov/pubmed/36986570 http://dx.doi.org/10.3390/ph16030470

Ejemplares similares

Long-Term Effects of Suramin on Renal Function in Streptozotocin-Induced Diabetes in Rats
por: Chyła-Danił, Gabriela, et al.
Publicado: (2023)

Suramin enhances the urinary excretion of VEGF-A in normoglycemic and streptozotocin-induced diabetic rats
por: Chyła, Gabriela, et al.
Publicado: (2021)

Redox regulation of hemodynamics response to diadenosine tetraphosphate an agonist of P2 receptors and renal function in diet‐induced hypercholesterolemic rats
por: Dąbkowski, Kamil, et al.
Publicado: (2021)

Lipid Profile, Lp(a) Levels, and HDL Quality in Adolescents with Down Syndrome
por: Krzesińska, Aleksandra, et al.
Publicado: (2022)

Nanoparticle Tracking Analysis of Urinary Extracellular Vesicle Proteins as a New Challenge in Laboratory Medicine
por: Sałaga-Zaleska, Kornelia, et al.
Publicado: (2023)

Analysis of Dietary Habits and Nutritional Status of Children with Down Syndrome in the Context of Lipid and Oxidative Stress Parameters
por: Wernio, Edyta, et al.
Publicado: (2022)

Lipoprotein(a) As a Potential Predictive Factor for Earlier Aortic Valve Replacement in Patients with Bicuspid Aortic Valve
por: Krzesińska, Aleksandra, et al.
Publicado: (2023)

Plasma Levels of Preβ1-HDL Are Significantly Elevated in Non-Dialyzed Patients with Advanced Stages of Chronic Kidney Disease
por: Kuchta, Agnieszka, et al.
Publicado: (2019)

Apolipoprotein E gene polymorphism and renal function are associated with apolipoprotein E concentration in patients with chronic kidney disease
por: Czaplińska, Monika, et al.
Publicado: (2019)

VEGF-VEGFR Signals in Health and Disease
por: Shibuya, Masabumi
Publicado: (2014)

Rapamycin suppresses angiogenesis and lymphangiogenesis in melanoma by downregulating VEGF-A/VEGFR-2 and VEGF-C/VEGFR-3 expression
por: Wang, Min, et al.
Publicado: (2019)

Changes in the Expression Profile of VEGF-A, VEGF-B, VEGFR-1, VEGFR-2 in Different Grades of Endometrial Cancer
por: Dziobek, Konrad, et al.
Publicado: (2019)

Molecular Targeting of VEGF with a Suramin Fragment–DOCA Conjugate by Mimicking the Action of Low Molecular Weight Heparins
por: Park, Jooho, et al.
Publicado: (2020)

Targeting VEGF/VEGFR to Modulate Antitumor Immunity
por: Yang, Ju, et al.
Publicado: (2018)

Diagnostic Value of VEGF-A, VEGFR-1 and VEGFR-2 in Feline Mammary Carcinoma
por: Nascimento, Catarina, et al.
Publicado: (2021)

VEGF-dependent tumor angiogenesis requires the inverse and reciprocal regulation of VEGFR1 and VEGFR2
por: Zhang, Zhaocheng, et al.
Publicado: (2009)

Genetic variations in VEGF and VEGFR2 and glioblastoma outcome
por: Sjöström, S., et al.
Publicado: (2010)

Counterbalance: modulation of VEGF/VEGFR activities by TNFSF15
por: Yang, Gui-Li, et al.
Publicado: (2018)

The VEGF/VEGFR Axis Revisited: Implications for Cancer Therapy
por: Mabeta, Peace, et al.
Publicado: (2022)

Structure-Based Design of Peptides Targeting VEGF/VEGFRs
por: Di Stasi, Rossella, et al.
Publicado: (2023)

Suramin: A Potential Therapy for Diabetic Nephropathy
por: Korrapati, Midhun C., et al.
Publicado: (2013)

Suramin Inhibits Chikungunya Virus Entry and Transmission
por: Ho, Yi-Jung, et al.
Publicado: (2015)

Role of Energy Metabolism in the Progression of Neuroblastoma
por: Sakowicz-Burkiewicz, Monika, et al.
Publicado: (2021)

The Impact of Lipoprotein Apheresis on Oxidative Stress Biomarkers and High-Density Lipoprotein Subfractions
por: Mickiewicz, Agnieszka, et al.
Publicado: (2020)

Human Plasma Levels of VEGF-A, VEGF-C, VEGF-D, their Soluble Receptor - VEGFR-2 and Applicability of these Parameters as Tumor Markers in the Diagnostics of Breast Cancer
por: Zajkowska, Monika, et al.
Publicado: (2018)

Effects of oestradiol and tamoxifen on VEGF, soluble VEGFR-1, and VEGFR-2 in breast cancer and endothelial cells
por: Garvin, S, et al.
Publicado: (2005)

The role of the VEGF-C/VEGFR-3 axis in cancer progression
por: Su, J-L, et al.
Publicado: (2007)

The Role of the VEGF-C/VEGFRs Axis in Tumor Progression and Therapy
por: Chen, Jui-Chieh, et al.
Publicado: (2012)

Relationship of VEGF/VEGFR with immune and cancer cells: staggering or forward?
por: Li, Yu-Ling, et al.
Publicado: (2016)

VEGF-A splice variants bind VEGFRs with differential affinities
por: Mamer, Spencer B., et al.
Publicado: (2020)

Inhibition of FGF‐FGFR and VEGF‐VEGFR signalling in cancer treatment
por: Liu, Guihong, et al.
Publicado: (2021)

Suramin Alleviates Glomerular Injury and Inflammation in the Remnant Kidney
por: Liu, Na, et al.
Publicado: (2012)

Suramin Inhibits Hsp104 ATPase and Disaggregase Activity
por: Torrente, Mariana P., et al.
Publicado: (2014)

Correction: Suramin: A Potential Therapy for Diabetic Nephropathy
Publicado: (2014)

Suramin-Induced Neurotoxicity: Preclinical Models and Neuroprotective Strategies
por: von der Ahe, David, et al.
Publicado: (2018)

Delayed administration of suramin attenuates peritoneal fibrosis in rats
por: Xiong, Chongxiang, et al.
Publicado: (2019)

1984—Discovery of the First Anti-HIV Drug, Suramin
por: De Clercq, Erik
Publicado: (2021)

Association between intratumoral free and total VEGF, soluble VEGFR-1, VEGFR-2 and prognosis in breast cancer
por: Bando, H, et al.
Publicado: (2005)

Profiling of VEGFs and VEGFRs as Prognostic Factors in Soft Tissue Sarcoma: VEGFR-3 Is an Independent Predictor of Poor Prognosis
por: Kilvaer, Thomas K., et al.
Publicado: (2010)

Expression of TNF-α, OPG, IL-1β and the presence of the measles virus RNA in the stapes of the patients with otosclerosis
por: Potocka-Bakłażec, Małgorzata, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_h4n794pf1odra971hrjqc6k2hn