Cargando…

Development of Novel Microwell-Based Spectrofluorimetry and High-Performance Liquid Chromatography with Fluorescence Detection Methods and High Throughput for Quantitation of Alectinib in Bulk Powder and Urine Samples

Background and Objectives: This study presents the development and validation of the 96-microwell-based spectrofluorimetric (MW-SFL) and high performance liquid chromatography (HPLC) with fluorescence detection (HPLC-FD) methods for the quantitation of alectinib (ALC) in its bulk powder form and in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Almutairi, Halah S., Alanazi, Mohammed M., Darwish, Ibrahim A., Bakheit, Ahmed H., Alshehri, Mona M., Darwish, Hany W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053830/ https://www.ncbi.nlm.nih.gov/pubmed/36984441 http://dx.doi.org/10.3390/medicina59030441

Ejemplares similares

Charge Transfer Complex of Lorlatinib with Chloranilic Acid: Characterization and Application to the Development of a Novel 96-Microwell Spectrophotometric Assay with High Throughput
por: Darwish, Hany W., et al.
Publicado: (2023)

Development of Novel Micellar-Enhanced High-Throughput Microwell Spectrofluorimetric Method for Quantification of Lorlatinib: Application to In Vitro Drug Release and Analysis of Urine Samples
por: Al-Hossaini, Abdullah M., et al.
Publicado: (2023)

Spectrophotometric Investigations of Charge Transfer Complexes of Tyrosine Kinase Inhibitors with Iodine as a σ-Electron Acceptor: Application to Development of Universal High-Throughput Microwell Assay for Their Determination in Pharmaceutical Formulations
por: Darwish, Ibrahim A., et al.
Publicado: (2023)

One-Step Microwell Plate-Based Spectrofluorimetric Assay for Direct Determination of Statins in Bulk Forms and Pharmaceutical Formulations: A Green Eco-Friendly and High-Throughput Analytical Approach
por: Darwish, Ibrahim A., et al.
Publicado: (2023)

Novel High-Throughput Microwell Spectrophotometric Assay for One-Step Determination of Lorlatinib, a Novel Potent Drug for the Treatment of Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer
por: Al-Hossaini, Abdullah M., et al.
Publicado: (2023)

Development and Validation of Green and High-Throughput Microwell Spectrophotometric Assay for the Determination of Selective Serotonin Reuptake Inhibitors in Their Pharmaceutical Dosage Forms
por: Darwish, Ibrahim A., et al.
Publicado: (2023)

Determination of galantamine hydrobromide in bulk drug and pharmaceutical dosage form by spectrofluorimetry
por: Patel, Amit V., et al.
Publicado: (2013)

Development of a novel 96-microwell assay with high throughput for determination of olmesartan medoxomil in its tablets
por: Darwish, Ibrahim A, et al.
Publicado: (2012)

Development of a Green Microwell Spectrofluorimetric Assay with High Analytical Throughput for the Determination of Selective Serotonin Reuptake Inhibitors in Pharmaceutical Dosage Forms and Plasma
por: Alzoman, Nourah Z., et al.
Publicado: (2023)

Novel microwell assay with high throughput and minimum consumption for organic solvents in the charge transfer-based spectrophotometric determination of clarithromycin in pharmaceutical formulations
por: Darwish, Ibrahim A, et al.
Publicado: (2013)

Development of Green and High Throughput Microplate Reader-Assisted Universal Microwell Spectrophotometric Assay for Direct Determination of Tyrosine Kinase Inhibitors in Their Pharmaceutical Formulations Irrespective the Diversity of Their Chemical Structures
por: Darwish, Ibrahim A., et al.
Publicado: (2023)

Validated liquid chromatography tandem mass spectrometry for simultaneous quantification of foretinib and lapatinib, and application to metabolic stability investigation
por: Alanazi, Mohammed M., et al.
Publicado: (2019)

A highly sensitive fluorimetric method for determination of lenalidomide in its bulk form and capsules via derivatization with fluorescamine
por: Darwish, Ibrahim A, et al.
Publicado: (2012)

Experimental and Computational Evaluation of Chloranilic Acid as an Universal Chromogenic Reagent for the Development of a Novel 96-Microwell Spectrophotometric Assay for Tyrosine Kinase Inhibitors
por: Darwish, Ibrahim A., et al.
Publicado: (2021)

Synthesis, spectroscopic and computational characterization of charge transfer complex of remdesivir with chloranilic acid: Application to development of novel 96-microwell spectrophotometric assay
por: Darwish, Ibrahim A., et al.
Publicado: (2022)

Marrying microfluidics and microwells for parallel, high-throughput single-cell genomics
por: Wadsworth, Marc H., et al.
Publicado: (2015)

High-throughput feedback-enabled optogenetic stimulation and spectroscopy in microwell plates
por: Benman, William, et al.
Publicado: (2023)

Micellar Enhanced Spectrofluorimetric Method for the Determination of Ponatinib in Human Plasma and Urine via Cremophor RH 40 as Sensing Agent
por: Darwish, Hany W., et al.
Publicado: (2015)

Experimental and computational evaluation of kolliphor RH 40 as a new fluorescence enhancer in development of a micellar-based spectrofluorimetric method for determination of lapatinib in tablets and urine
por: Darwish, Hany W., et al.
Publicado: (2020)

Development of Two Novel One-Step and Green Microwell Spectrophotometric Methods for High-Throughput Determination of Ceritinib, a Potent Drug for Treatment of Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer
por: Abuhejail, Reem M., et al.
Publicado: (2023)

Three Innovative Green and High-Throughput Microwell Spectrophotometric Methods for the Quantitation of Ceritinib, a Potent Drug for the Treatment of ALK-Positive Non-Small Cell Lung Cancer: An Application to the Analysis of Capsules and Drug Uniformity Testing
por: Abuhejail, Reem M., et al.
Publicado: (2023)

Characterization of in vivo metabolites in rat urine following an oral dose of masitinib by liquid chromatography tandem mass spectrometry
por: Kadi, Adnan A., et al.
Publicado: (2018)

A novel micro-extraction strategy for extraction of bisphosphonates from biological fluids using zirconia nanoparticles coupled with spectrofluorimetry and high performance liquid chromatography
por: Rahbar, Nadereh, et al.
Publicado: (2018)

High-throughput Microwell-seq 2.0 profiles massively multiplexed chemical perturbation
por: Chen, Haide, et al.
Publicado: (2021)

High Throughput 3D Cell Migration Assay Using Micropillar/Microwell Chips
por: Lee, Sang-Yun, et al.
Publicado: (2022)

High throughput, label-free isolation of circulating tumor cell clusters in meshed microwells
por: Boya, Mert, et al.
Publicado: (2022)

High-throughput spatiotemporal monitoring of single-cell secretions via plasmonic microwell arrays
por: Ansaryan, Saeid, et al.
Publicado: (2023)

Effect of downscaling on the linearity range of a calibration curve in spectrofluorimetry
por: Kwapiszewski, Radoslaw, et al.
Publicado: (2014)

Comparative ANNs with Different Input Layers and GA-PLS Study for Simultaneous Spectrofluorimetric Determination of Melatonin and Pyridoxine HCl in the Presence of Melatonin’s Main Impurity
por: Darwish, Hany W., et al.
Publicado: (2013)

Remdesivir
por: Bakheit, Ahmed H., et al.
Publicado: (2023)

Novel microwell-based spectrophotometric assay for determination of atorvastatin calcium in its pharmaceutical formulations
por: Wani, Tanveer A, et al.
Publicado: (2011)

Determination of sildenafil by preconcentration on surfactant coated polymeric resin followed by spectrofluorimetry()
por: Wang, Chien C., et al.
Publicado: (2013)

The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform
por: Mosaad, E. O., et al.
Publicado: (2018)

High-throughput live-imaging of embryos in microwell arrays using a modular specimen mounting system
por: Donoughe, Seth, et al.
Publicado: (2018)

Nanoliter Centrifugal Liquid Dispenser Coupled with Superhydrophobic Microwell Array Chips for High-Throughput Cell Assays
por: Wang, Yuyi, et al.
Publicado: (2018)

Microwell Plate-Based Dynamic Light Scattering as a High-Throughput Characterization Tool in Biopharmaceutical Development
por: Dauer, Katharina, et al.
Publicado: (2021)

Comparative Study of Novel Ratio Spectra and Isoabsorptive Point Based Spectrophotometric Methods: Application on a Binary Mixture of Ascorbic Acid and Rutin
por: Darwish, Hany W., et al.
Publicado: (2016)

Teflon-on-Glass Molding Enables High-Throughput Fabrication of Hydrophilic-in-Hydrophobic Microwells for Bead-Based Digital Bioassays
por: Tripodi, Lisa, et al.
Publicado: (2018)

A High-Throughput Single-Clone Phage Fluorescence Microwell Immunoassay and Laser-Driven Clonal Retrieval System
por: Chang, Seohee, et al.
Publicado: (2020)

O-(β-hydroxyethyl)rutosides determination by micellar flow injection (FI)-spectrofluorimetry
por: Peralta, Cecilia Mariana, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5gg4jvs6qfroqvr3ea14ajajnk