Cargando…
Counteracting Colon Cancer by Inhibiting Mitochondrial Respiration and Glycolysis with a Selective PKCδ Activator
Metabolic reprogramming is a central hub in tumor development and progression. Therefore, several efforts have been developed to find improved therapeutic approaches targeting cancer cell metabolism. Recently, we identified the 7α-acetoxy-6β-benzoyloxy-12-O-benzoylroyleanone (Roy-Bz) as a PKCδ-selec...
Autores principales: | Bessa, Cláudia, Loureiro, Joana B., Barros, Matilde, Isca, Vera M. S., Sardão, Vilma A., Oliveira, Paulo J., Bernardino, Raquel L., Herman-de-Sousa, Carina, Costa, Maria Adelina, Correia-de-Sá, Paulo, Alves, Marco G., Rijo, Patrícia, Saraiva, Lucília |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054007/ https://www.ncbi.nlm.nih.gov/pubmed/36982784 http://dx.doi.org/10.3390/ijms24065710 |
Ejemplares similares
-
PKCα and PKCδ: Friends and Rivals
por: Black, Jennifer D., et al.
Publicado: (2022) -
Discovery of a small-molecule protein kinase Cδ-selective activator with promising application in colon cancer therapy
por: Bessa, Cláudia, et al.
Publicado: (2018) -
The Nutraceutic Silybin Counteracts Excess Lipid Accumulation and Ongoing Oxidative Stress in an In Vitro Model of Non-Alcoholic Fatty Liver Disease Progression
por: Vecchione, Giulia, et al.
Publicado: (2017) -
Differential Roles of the PKC Novel Isoforms, PKCδ and PKCε, in Mouse and Human Platelets
por: Pears, Catherine J., et al.
Publicado: (2008) -
PKCδ Blues for the β-Cell
por: Schmitz-Peiffer, Carsten, et al.
Publicado: (2010)