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Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission

In the past decade, novel nano-engineering protocols have been actively synergized with fluorescence spectroscopic techniques to yield higher intensity from radiating dipoles, through the process termed plasmon-enhanced fluorescence (PEF). Consequently, the limit of detection of analytes of interest...

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Autor principal: Bhaskar, Seemesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054051/
https://www.ncbi.nlm.nih.gov/pubmed/36984981
http://dx.doi.org/10.3390/mi14030574
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author Bhaskar, Seemesh
author_facet Bhaskar, Seemesh
author_sort Bhaskar, Seemesh
collection PubMed
description In the past decade, novel nano-engineering protocols have been actively synergized with fluorescence spectroscopic techniques to yield higher intensity from radiating dipoles, through the process termed plasmon-enhanced fluorescence (PEF). Consequently, the limit of detection of analytes of interest has been dramatically improvised on account of higher sensitivity rendered by augmented fluorescence signals. Recently, metallic thin films sustaining surface plasmon polaritons (SPPs) have been creatively hybridized with such PEF platforms to realize a substantial upsurge in the global collection efficiency in a judicious technology termed surface plasmon-coupled emission (SPCE). While the process parameters and conditions to realize optimum coupling efficiency between the radiating dipoles and the plasmon polaritons in SPCE framework have been extensively discussed, the utility of disruptive nano-engineering over the SPCE platform and analogous interfaces such as ‘ferroplasmon-on-mirror (FPoM)’ as well as an alternative technology termed ‘photonic crystal-coupled emission (PCCE)’ have been seldom reviewed. In light of these observations, in this focus review, the myriad nano-engineering protocols developed over the SPCE, FPoM and PCCE platform are succinctly captured, presenting an emphasis on the recently developed cryosoret nano-assembly technology for photo-plasmonic hotspot generation (first to fourth). These technologies and associated sensing platforms are expected to ameliorate the current biosensing modalities with better understanding of the biophysicochemical processes and related outcomes at advanced micro-nano-interfaces. This review is hence envisaged to present a broad overview of the latest developments in SPCE substrate design and development for interdisciplinary applications that are of relevance in environmental as well as biological heath monitoring.
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spelling pubmed-100540512023-03-30 Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission Bhaskar, Seemesh Micromachines (Basel) Review In the past decade, novel nano-engineering protocols have been actively synergized with fluorescence spectroscopic techniques to yield higher intensity from radiating dipoles, through the process termed plasmon-enhanced fluorescence (PEF). Consequently, the limit of detection of analytes of interest has been dramatically improvised on account of higher sensitivity rendered by augmented fluorescence signals. Recently, metallic thin films sustaining surface plasmon polaritons (SPPs) have been creatively hybridized with such PEF platforms to realize a substantial upsurge in the global collection efficiency in a judicious technology termed surface plasmon-coupled emission (SPCE). While the process parameters and conditions to realize optimum coupling efficiency between the radiating dipoles and the plasmon polaritons in SPCE framework have been extensively discussed, the utility of disruptive nano-engineering over the SPCE platform and analogous interfaces such as ‘ferroplasmon-on-mirror (FPoM)’ as well as an alternative technology termed ‘photonic crystal-coupled emission (PCCE)’ have been seldom reviewed. In light of these observations, in this focus review, the myriad nano-engineering protocols developed over the SPCE, FPoM and PCCE platform are succinctly captured, presenting an emphasis on the recently developed cryosoret nano-assembly technology for photo-plasmonic hotspot generation (first to fourth). These technologies and associated sensing platforms are expected to ameliorate the current biosensing modalities with better understanding of the biophysicochemical processes and related outcomes at advanced micro-nano-interfaces. This review is hence envisaged to present a broad overview of the latest developments in SPCE substrate design and development for interdisciplinary applications that are of relevance in environmental as well as biological heath monitoring. MDPI 2023-02-28 /pmc/articles/PMC10054051/ /pubmed/36984981 http://dx.doi.org/10.3390/mi14030574 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bhaskar, Seemesh
Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission
title Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission
title_full Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission
title_fullStr Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission
title_full_unstemmed Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission
title_short Biosensing Technologies: A Focus Review on Recent Advancements in Surface Plasmon Coupled Emission
title_sort biosensing technologies: a focus review on recent advancements in surface plasmon coupled emission
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054051/
https://www.ncbi.nlm.nih.gov/pubmed/36984981
http://dx.doi.org/10.3390/mi14030574
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