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Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?

Spray drying is one of the most frequently used solvent-based processes for manufacturing amorphous solid dispersions (ASDs). However, the resulting fine powders usually require further downstream processing when intended for solid oral dosage forms. In this study, we compare properties and performa...

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Detalles Bibliográficos
Autores principales: Neuwirth, Marius, Kappes, Sebastian K., Hartig, Michael U., Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054131/
https://www.ncbi.nlm.nih.gov/pubmed/36986625
http://dx.doi.org/10.3390/pharmaceutics15030764