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Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers’ Lactamization

The concept of privileged structure has been used as a fruitful approach for the discovery of novel biologically active molecules. A privileged structure is defined as a semi-rigid scaffold able to display substituents in multiple spatial directions and capable of providing potent and selective liga...

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Detalles Bibliográficos
Autores principales: Tangara, Salia, Faïon, Léo, Piveteau, Catherine, Capet, Frédéric, Godelier, Romain, Michel, Marion, Flipo, Marion, Deprez, Benoit, Willand, Nicolas, Villemagne, Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054226/
https://www.ncbi.nlm.nih.gov/pubmed/36986512
http://dx.doi.org/10.3390/ph16030413