Pharmacological Chaperones and Protein Conformational Diseases: Approaches of Computational Structural Biology

Whenever a protein fails to fold into its native structure, a profound detrimental effect is likely to occur, and a disease is often developed. Protein conformational disorders arise when proteins adopt abnormal conformations due to a pathological gene variant that turns into gain/loss of function o...

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Detalles Bibliográficos
Autores principales: Grasso, Daniela, Galderisi, Silvia, Santucci, Annalisa, Bernini, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054308/
https://www.ncbi.nlm.nih.gov/pubmed/36982893
http://dx.doi.org/10.3390/ijms24065819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054308/
https://www.ncbi.nlm.nih.gov/pubmed/36982893
http://dx.doi.org/10.3390/ijms24065819

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