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Pharmacological Chaperones and Protein Conformational Diseases: Approaches of Computational Structural Biology
Whenever a protein fails to fold into its native structure, a profound detrimental effect is likely to occur, and a disease is often developed. Protein conformational disorders arise when proteins adopt abnormal conformations due to a pathological gene variant that turns into gain/loss of function o...
Autores principales: | Grasso, Daniela, Galderisi, Silvia, Santucci, Annalisa, Bernini, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054308/ https://www.ncbi.nlm.nih.gov/pubmed/36982893 http://dx.doi.org/10.3390/ijms24065819 |
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