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Maresin1 Ameliorates Sepsis-Induced Microglial Neuritis Induced through Blocking TLR4-NF-κ B-NLRP3 Signaling Pathway

Objective: Neuroinflammation is a major etiology of cognitive dysfunction due to sepsis. Maresin1 (MaR1), identified as a docosahexaenoic acid (DHA)-derived metabolite from macrophages, has been demonstrated to exhibit potent neuroprotective and anti-inflammatory effects. Nevertheless, detailed func...

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Detalles Bibliográficos
Autores principales: Wu, Huiping, Wang, Ying, Fu, Haiyan, Ji, Lili, Li, Na, Zhang, Dan, Su, Longxiang, Hu, Zhansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054512/
https://www.ncbi.nlm.nih.gov/pubmed/36983716
http://dx.doi.org/10.3390/jpm13030534