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Recent Advances in Synthetic Routes to Azacycles

A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycle...

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Detalles Bibliográficos
Autores principales: Nguyen, Anh Thu, Kim, Hee-Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054516/
https://www.ncbi.nlm.nih.gov/pubmed/36985708
http://dx.doi.org/10.3390/molecules28062737
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author Nguyen, Anh Thu
Kim, Hee-Kwon
author_facet Nguyen, Anh Thu
Kim, Hee-Kwon
author_sort Nguyen, Anh Thu
collection PubMed
description A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycles have received significant attention from scientists and a variety of methods of synthesizing azacycles have been developed because their efficient synthesis plays a vital role in the production of many useful compounds. In this review, we summarize recent approaches to preparing azacycles via different methods as well as describe plausible reaction mechanisms.
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spelling pubmed-100545162023-03-30 Recent Advances in Synthetic Routes to Azacycles Nguyen, Anh Thu Kim, Hee-Kwon Molecules Review A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycles have received significant attention from scientists and a variety of methods of synthesizing azacycles have been developed because their efficient synthesis plays a vital role in the production of many useful compounds. In this review, we summarize recent approaches to preparing azacycles via different methods as well as describe plausible reaction mechanisms. MDPI 2023-03-17 /pmc/articles/PMC10054516/ /pubmed/36985708 http://dx.doi.org/10.3390/molecules28062737 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nguyen, Anh Thu
Kim, Hee-Kwon
Recent Advances in Synthetic Routes to Azacycles
title Recent Advances in Synthetic Routes to Azacycles
title_full Recent Advances in Synthetic Routes to Azacycles
title_fullStr Recent Advances in Synthetic Routes to Azacycles
title_full_unstemmed Recent Advances in Synthetic Routes to Azacycles
title_short Recent Advances in Synthetic Routes to Azacycles
title_sort recent advances in synthetic routes to azacycles
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054516/
https://www.ncbi.nlm.nih.gov/pubmed/36985708
http://dx.doi.org/10.3390/molecules28062737
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