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Recent Advances in Synthetic Routes to Azacycles
A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycle...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054516/ https://www.ncbi.nlm.nih.gov/pubmed/36985708 http://dx.doi.org/10.3390/molecules28062737 |
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author | Nguyen, Anh Thu Kim, Hee-Kwon |
author_facet | Nguyen, Anh Thu Kim, Hee-Kwon |
author_sort | Nguyen, Anh Thu |
collection | PubMed |
description | A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycles have received significant attention from scientists and a variety of methods of synthesizing azacycles have been developed because their efficient synthesis plays a vital role in the production of many useful compounds. In this review, we summarize recent approaches to preparing azacycles via different methods as well as describe plausible reaction mechanisms. |
format | Online Article Text |
id | pubmed-10054516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100545162023-03-30 Recent Advances in Synthetic Routes to Azacycles Nguyen, Anh Thu Kim, Hee-Kwon Molecules Review A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycles have received significant attention from scientists and a variety of methods of synthesizing azacycles have been developed because their efficient synthesis plays a vital role in the production of many useful compounds. In this review, we summarize recent approaches to preparing azacycles via different methods as well as describe plausible reaction mechanisms. MDPI 2023-03-17 /pmc/articles/PMC10054516/ /pubmed/36985708 http://dx.doi.org/10.3390/molecules28062737 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Nguyen, Anh Thu Kim, Hee-Kwon Recent Advances in Synthetic Routes to Azacycles |
title | Recent Advances in Synthetic Routes to Azacycles |
title_full | Recent Advances in Synthetic Routes to Azacycles |
title_fullStr | Recent Advances in Synthetic Routes to Azacycles |
title_full_unstemmed | Recent Advances in Synthetic Routes to Azacycles |
title_short | Recent Advances in Synthetic Routes to Azacycles |
title_sort | recent advances in synthetic routes to azacycles |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054516/ https://www.ncbi.nlm.nih.gov/pubmed/36985708 http://dx.doi.org/10.3390/molecules28062737 |
work_keys_str_mv | AT nguyenanhthu recentadvancesinsyntheticroutestoazacycles AT kimheekwon recentadvancesinsyntheticroutestoazacycles |