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Inhibiting Leishmania donovani Sterol Methyltransferase to Identify Lead Compounds Using Molecular Modelling

The recent outlook of leishmaniasis as a global public health concern coupled with the reportage of resistance and lack of efficacy of most antileishmanial drugs calls for a concerted effort to find new leads. The study combined In silico and in vitro approaches to identify novel potential synthetic...

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Detalles Bibliográficos
Autores principales: Sakyi, Patrick O., Kwofie, Samuel K., Tuekpe, Julius K., Gwira, Theresa M., Broni, Emmanuel, Miller, Whelton A., Wilson, Michael D., Amewu, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054574/
https://www.ncbi.nlm.nih.gov/pubmed/36986430
http://dx.doi.org/10.3390/ph16030330