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Inhibiting Leishmania donovani Sterol Methyltransferase to Identify Lead Compounds Using Molecular Modelling
The recent outlook of leishmaniasis as a global public health concern coupled with the reportage of resistance and lack of efficacy of most antileishmanial drugs calls for a concerted effort to find new leads. The study combined In silico and in vitro approaches to identify novel potential synthetic...
Autores principales: | Sakyi, Patrick O., Kwofie, Samuel K., Tuekpe, Julius K., Gwira, Theresa M., Broni, Emmanuel, Miller, Whelton A., Wilson, Michael D., Amewu, Richard K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054574/ https://www.ncbi.nlm.nih.gov/pubmed/36986430 http://dx.doi.org/10.3390/ph16030330 |
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