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Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture

The number of elderly patients with cervical trauma is increasing. Such patients are considered to be at high risk for delirium, which is an acute neuropsychological disorder that reduces the patient’s capacity to interact with their environment due to impairments in cognition. This study aimed to e...

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Autores principales: Tamai, Koji, Terai, Hidetomi, Nakamura, Hiroaki, Yokogawa, Noriaki, Sasagawa, Takeshi, Nakashima, Hiroaki, Segi, Naoki, Ito, Sadayuki, Funayama, Toru, Eto, Fumihiko, Yamaji, Akihiro, Watanabe, Kota, Yamane, Junichi, Takeda, Kazuki, Furuya, Takeo, Yunde, Atsushi, Nakajima, Hideaki, Yamada, Tomohiro, Hasegawa, Tomohiko, Terashima, Yoshinori, Hirota, Ryosuke, Suzuki, Hidenori, Imajo, Yasuaki, Ikegami, Shota, Uehara, Masashi, Tonomura, Hitoshi, Sakata, Munehiro, Hashimoto, Ko, Onoda, Yoshito, Kawaguchi, Kenichi, Haruta, Yohei, Suzuki, Nobuyuki, Kato, Kenji, Uei, Hiroshi, Sawada, Hirokatsu, Nakanishi, Kazuo, Misaki, Kosuke, Kuroda, Akiyoshi, Inoue, Gen, Kakutani, Kenichiro, Kakiuchi, Yuji, Kiyasu, Katsuhito, Tominaga, Hiroyuki, Tokumoto, Hiroto, Iizuka, Yoichi, Takasawa, Eiji, Akeda, Koji, Takegami, Norihiko, Funao, Haruki, Oshima, Yasushi, Kaito, Takashi, Sakai, Daisuke, Yoshii, Toshitaka, Ohba, Tetsuro, Otsuki, Bungo, Seki, Shoji, Miyazaki, Masashi, Ishihara, Masayuki, Okada, Seiji, Imagama, Shiro, Kato, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054626/
https://www.ncbi.nlm.nih.gov/pubmed/36983387
http://dx.doi.org/10.3390/jcm12062387
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author Tamai, Koji
Terai, Hidetomi
Nakamura, Hiroaki
Yokogawa, Noriaki
Sasagawa, Takeshi
Nakashima, Hiroaki
Segi, Naoki
Ito, Sadayuki
Funayama, Toru
Eto, Fumihiko
Yamaji, Akihiro
Watanabe, Kota
Yamane, Junichi
Takeda, Kazuki
Furuya, Takeo
Yunde, Atsushi
Nakajima, Hideaki
Yamada, Tomohiro
Hasegawa, Tomohiko
Terashima, Yoshinori
Hirota, Ryosuke
Suzuki, Hidenori
Imajo, Yasuaki
Ikegami, Shota
Uehara, Masashi
Tonomura, Hitoshi
Sakata, Munehiro
Hashimoto, Ko
Onoda, Yoshito
Kawaguchi, Kenichi
Haruta, Yohei
Suzuki, Nobuyuki
Kato, Kenji
Uei, Hiroshi
Sawada, Hirokatsu
Nakanishi, Kazuo
Misaki, Kosuke
Kuroda, Akiyoshi
Inoue, Gen
Kakutani, Kenichiro
Kakiuchi, Yuji
Kiyasu, Katsuhito
Tominaga, Hiroyuki
Tokumoto, Hiroto
Iizuka, Yoichi
Takasawa, Eiji
Akeda, Koji
Takegami, Norihiko
Funao, Haruki
Oshima, Yasushi
Kaito, Takashi
Sakai, Daisuke
Yoshii, Toshitaka
Ohba, Tetsuro
Otsuki, Bungo
Seki, Shoji
Miyazaki, Masashi
Ishihara, Masayuki
Okada, Seiji
Imagama, Shiro
Kato, Satoshi
author_facet Tamai, Koji
Terai, Hidetomi
Nakamura, Hiroaki
Yokogawa, Noriaki
Sasagawa, Takeshi
Nakashima, Hiroaki
Segi, Naoki
Ito, Sadayuki
Funayama, Toru
Eto, Fumihiko
Yamaji, Akihiro
Watanabe, Kota
Yamane, Junichi
Takeda, Kazuki
Furuya, Takeo
Yunde, Atsushi
Nakajima, Hideaki
Yamada, Tomohiro
Hasegawa, Tomohiko
Terashima, Yoshinori
Hirota, Ryosuke
Suzuki, Hidenori
Imajo, Yasuaki
Ikegami, Shota
Uehara, Masashi
Tonomura, Hitoshi
Sakata, Munehiro
Hashimoto, Ko
Onoda, Yoshito
Kawaguchi, Kenichi
Haruta, Yohei
Suzuki, Nobuyuki
Kato, Kenji
Uei, Hiroshi
Sawada, Hirokatsu
Nakanishi, Kazuo
Misaki, Kosuke
Kuroda, Akiyoshi
Inoue, Gen
Kakutani, Kenichiro
Kakiuchi, Yuji
Kiyasu, Katsuhito
Tominaga, Hiroyuki
Tokumoto, Hiroto
Iizuka, Yoichi
Takasawa, Eiji
Akeda, Koji
Takegami, Norihiko
Funao, Haruki
Oshima, Yasushi
Kaito, Takashi
Sakai, Daisuke
Yoshii, Toshitaka
Ohba, Tetsuro
Otsuki, Bungo
Seki, Shoji
Miyazaki, Masashi
Ishihara, Masayuki
Okada, Seiji
Imagama, Shiro
Kato, Satoshi
author_sort Tamai, Koji
collection PubMed
description The number of elderly patients with cervical trauma is increasing. Such patients are considered to be at high risk for delirium, which is an acute neuropsychological disorder that reduces the patient’s capacity to interact with their environment due to impairments in cognition. This study aimed to establish a risk score that predicts delirium in elderly patients with cervical SCI and/or cervical fracture regardless of treatment type. This retrospective cohort study included 1512 patients aged ≥65 years with cervical SCI and/or cervical fracture. The risk factors for delirium according to treatment type (surgical or conservative) were calculated using multivariate logistic regression. A delirium risk score was established as the simple arithmetic sum of points assigned to variables that were significant in the multivariate analyses. Based on the statistical results, the delirium risk score was defined using six factors: old age (≥80 years), hypoalbuminemia, cervical fracture, major organ injury, dependence on pre-injury mobility, and comorbid diabetes. The score’s area under the curve for the prediction of delirium was 0.66 (p < 0.001). Although the current scoring system must be validated with an independent dataset, the system remains beneficial because it can be used after screening examinations upon hospitalization and before deciding the treatment strategy.
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spelling pubmed-100546262023-03-30 Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture Tamai, Koji Terai, Hidetomi Nakamura, Hiroaki Yokogawa, Noriaki Sasagawa, Takeshi Nakashima, Hiroaki Segi, Naoki Ito, Sadayuki Funayama, Toru Eto, Fumihiko Yamaji, Akihiro Watanabe, Kota Yamane, Junichi Takeda, Kazuki Furuya, Takeo Yunde, Atsushi Nakajima, Hideaki Yamada, Tomohiro Hasegawa, Tomohiko Terashima, Yoshinori Hirota, Ryosuke Suzuki, Hidenori Imajo, Yasuaki Ikegami, Shota Uehara, Masashi Tonomura, Hitoshi Sakata, Munehiro Hashimoto, Ko Onoda, Yoshito Kawaguchi, Kenichi Haruta, Yohei Suzuki, Nobuyuki Kato, Kenji Uei, Hiroshi Sawada, Hirokatsu Nakanishi, Kazuo Misaki, Kosuke Kuroda, Akiyoshi Inoue, Gen Kakutani, Kenichiro Kakiuchi, Yuji Kiyasu, Katsuhito Tominaga, Hiroyuki Tokumoto, Hiroto Iizuka, Yoichi Takasawa, Eiji Akeda, Koji Takegami, Norihiko Funao, Haruki Oshima, Yasushi Kaito, Takashi Sakai, Daisuke Yoshii, Toshitaka Ohba, Tetsuro Otsuki, Bungo Seki, Shoji Miyazaki, Masashi Ishihara, Masayuki Okada, Seiji Imagama, Shiro Kato, Satoshi J Clin Med Article The number of elderly patients with cervical trauma is increasing. Such patients are considered to be at high risk for delirium, which is an acute neuropsychological disorder that reduces the patient’s capacity to interact with their environment due to impairments in cognition. This study aimed to establish a risk score that predicts delirium in elderly patients with cervical SCI and/or cervical fracture regardless of treatment type. This retrospective cohort study included 1512 patients aged ≥65 years with cervical SCI and/or cervical fracture. The risk factors for delirium according to treatment type (surgical or conservative) were calculated using multivariate logistic regression. A delirium risk score was established as the simple arithmetic sum of points assigned to variables that were significant in the multivariate analyses. Based on the statistical results, the delirium risk score was defined using six factors: old age (≥80 years), hypoalbuminemia, cervical fracture, major organ injury, dependence on pre-injury mobility, and comorbid diabetes. The score’s area under the curve for the prediction of delirium was 0.66 (p < 0.001). Although the current scoring system must be validated with an independent dataset, the system remains beneficial because it can be used after screening examinations upon hospitalization and before deciding the treatment strategy. MDPI 2023-03-20 /pmc/articles/PMC10054626/ /pubmed/36983387 http://dx.doi.org/10.3390/jcm12062387 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tamai, Koji
Terai, Hidetomi
Nakamura, Hiroaki
Yokogawa, Noriaki
Sasagawa, Takeshi
Nakashima, Hiroaki
Segi, Naoki
Ito, Sadayuki
Funayama, Toru
Eto, Fumihiko
Yamaji, Akihiro
Watanabe, Kota
Yamane, Junichi
Takeda, Kazuki
Furuya, Takeo
Yunde, Atsushi
Nakajima, Hideaki
Yamada, Tomohiro
Hasegawa, Tomohiko
Terashima, Yoshinori
Hirota, Ryosuke
Suzuki, Hidenori
Imajo, Yasuaki
Ikegami, Shota
Uehara, Masashi
Tonomura, Hitoshi
Sakata, Munehiro
Hashimoto, Ko
Onoda, Yoshito
Kawaguchi, Kenichi
Haruta, Yohei
Suzuki, Nobuyuki
Kato, Kenji
Uei, Hiroshi
Sawada, Hirokatsu
Nakanishi, Kazuo
Misaki, Kosuke
Kuroda, Akiyoshi
Inoue, Gen
Kakutani, Kenichiro
Kakiuchi, Yuji
Kiyasu, Katsuhito
Tominaga, Hiroyuki
Tokumoto, Hiroto
Iizuka, Yoichi
Takasawa, Eiji
Akeda, Koji
Takegami, Norihiko
Funao, Haruki
Oshima, Yasushi
Kaito, Takashi
Sakai, Daisuke
Yoshii, Toshitaka
Ohba, Tetsuro
Otsuki, Bungo
Seki, Shoji
Miyazaki, Masashi
Ishihara, Masayuki
Okada, Seiji
Imagama, Shiro
Kato, Satoshi
Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture
title Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture
title_full Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture
title_fullStr Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture
title_full_unstemmed Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture
title_short Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture
title_sort delirium risk score in elderly patients with cervical spinal cord injury and/or cervical fracture
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054626/
https://www.ncbi.nlm.nih.gov/pubmed/36983387
http://dx.doi.org/10.3390/jcm12062387
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