Cargando…
Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture
The number of elderly patients with cervical trauma is increasing. Such patients are considered to be at high risk for delirium, which is an acute neuropsychological disorder that reduces the patient’s capacity to interact with their environment due to impairments in cognition. This study aimed to e...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054626/ https://www.ncbi.nlm.nih.gov/pubmed/36983387 http://dx.doi.org/10.3390/jcm12062387 |
_version_ | 1785015716234133504 |
---|---|
author | Tamai, Koji Terai, Hidetomi Nakamura, Hiroaki Yokogawa, Noriaki Sasagawa, Takeshi Nakashima, Hiroaki Segi, Naoki Ito, Sadayuki Funayama, Toru Eto, Fumihiko Yamaji, Akihiro Watanabe, Kota Yamane, Junichi Takeda, Kazuki Furuya, Takeo Yunde, Atsushi Nakajima, Hideaki Yamada, Tomohiro Hasegawa, Tomohiko Terashima, Yoshinori Hirota, Ryosuke Suzuki, Hidenori Imajo, Yasuaki Ikegami, Shota Uehara, Masashi Tonomura, Hitoshi Sakata, Munehiro Hashimoto, Ko Onoda, Yoshito Kawaguchi, Kenichi Haruta, Yohei Suzuki, Nobuyuki Kato, Kenji Uei, Hiroshi Sawada, Hirokatsu Nakanishi, Kazuo Misaki, Kosuke Kuroda, Akiyoshi Inoue, Gen Kakutani, Kenichiro Kakiuchi, Yuji Kiyasu, Katsuhito Tominaga, Hiroyuki Tokumoto, Hiroto Iizuka, Yoichi Takasawa, Eiji Akeda, Koji Takegami, Norihiko Funao, Haruki Oshima, Yasushi Kaito, Takashi Sakai, Daisuke Yoshii, Toshitaka Ohba, Tetsuro Otsuki, Bungo Seki, Shoji Miyazaki, Masashi Ishihara, Masayuki Okada, Seiji Imagama, Shiro Kato, Satoshi |
author_facet | Tamai, Koji Terai, Hidetomi Nakamura, Hiroaki Yokogawa, Noriaki Sasagawa, Takeshi Nakashima, Hiroaki Segi, Naoki Ito, Sadayuki Funayama, Toru Eto, Fumihiko Yamaji, Akihiro Watanabe, Kota Yamane, Junichi Takeda, Kazuki Furuya, Takeo Yunde, Atsushi Nakajima, Hideaki Yamada, Tomohiro Hasegawa, Tomohiko Terashima, Yoshinori Hirota, Ryosuke Suzuki, Hidenori Imajo, Yasuaki Ikegami, Shota Uehara, Masashi Tonomura, Hitoshi Sakata, Munehiro Hashimoto, Ko Onoda, Yoshito Kawaguchi, Kenichi Haruta, Yohei Suzuki, Nobuyuki Kato, Kenji Uei, Hiroshi Sawada, Hirokatsu Nakanishi, Kazuo Misaki, Kosuke Kuroda, Akiyoshi Inoue, Gen Kakutani, Kenichiro Kakiuchi, Yuji Kiyasu, Katsuhito Tominaga, Hiroyuki Tokumoto, Hiroto Iizuka, Yoichi Takasawa, Eiji Akeda, Koji Takegami, Norihiko Funao, Haruki Oshima, Yasushi Kaito, Takashi Sakai, Daisuke Yoshii, Toshitaka Ohba, Tetsuro Otsuki, Bungo Seki, Shoji Miyazaki, Masashi Ishihara, Masayuki Okada, Seiji Imagama, Shiro Kato, Satoshi |
author_sort | Tamai, Koji |
collection | PubMed |
description | The number of elderly patients with cervical trauma is increasing. Such patients are considered to be at high risk for delirium, which is an acute neuropsychological disorder that reduces the patient’s capacity to interact with their environment due to impairments in cognition. This study aimed to establish a risk score that predicts delirium in elderly patients with cervical SCI and/or cervical fracture regardless of treatment type. This retrospective cohort study included 1512 patients aged ≥65 years with cervical SCI and/or cervical fracture. The risk factors for delirium according to treatment type (surgical or conservative) were calculated using multivariate logistic regression. A delirium risk score was established as the simple arithmetic sum of points assigned to variables that were significant in the multivariate analyses. Based on the statistical results, the delirium risk score was defined using six factors: old age (≥80 years), hypoalbuminemia, cervical fracture, major organ injury, dependence on pre-injury mobility, and comorbid diabetes. The score’s area under the curve for the prediction of delirium was 0.66 (p < 0.001). Although the current scoring system must be validated with an independent dataset, the system remains beneficial because it can be used after screening examinations upon hospitalization and before deciding the treatment strategy. |
format | Online Article Text |
id | pubmed-10054626 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100546262023-03-30 Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture Tamai, Koji Terai, Hidetomi Nakamura, Hiroaki Yokogawa, Noriaki Sasagawa, Takeshi Nakashima, Hiroaki Segi, Naoki Ito, Sadayuki Funayama, Toru Eto, Fumihiko Yamaji, Akihiro Watanabe, Kota Yamane, Junichi Takeda, Kazuki Furuya, Takeo Yunde, Atsushi Nakajima, Hideaki Yamada, Tomohiro Hasegawa, Tomohiko Terashima, Yoshinori Hirota, Ryosuke Suzuki, Hidenori Imajo, Yasuaki Ikegami, Shota Uehara, Masashi Tonomura, Hitoshi Sakata, Munehiro Hashimoto, Ko Onoda, Yoshito Kawaguchi, Kenichi Haruta, Yohei Suzuki, Nobuyuki Kato, Kenji Uei, Hiroshi Sawada, Hirokatsu Nakanishi, Kazuo Misaki, Kosuke Kuroda, Akiyoshi Inoue, Gen Kakutani, Kenichiro Kakiuchi, Yuji Kiyasu, Katsuhito Tominaga, Hiroyuki Tokumoto, Hiroto Iizuka, Yoichi Takasawa, Eiji Akeda, Koji Takegami, Norihiko Funao, Haruki Oshima, Yasushi Kaito, Takashi Sakai, Daisuke Yoshii, Toshitaka Ohba, Tetsuro Otsuki, Bungo Seki, Shoji Miyazaki, Masashi Ishihara, Masayuki Okada, Seiji Imagama, Shiro Kato, Satoshi J Clin Med Article The number of elderly patients with cervical trauma is increasing. Such patients are considered to be at high risk for delirium, which is an acute neuropsychological disorder that reduces the patient’s capacity to interact with their environment due to impairments in cognition. This study aimed to establish a risk score that predicts delirium in elderly patients with cervical SCI and/or cervical fracture regardless of treatment type. This retrospective cohort study included 1512 patients aged ≥65 years with cervical SCI and/or cervical fracture. The risk factors for delirium according to treatment type (surgical or conservative) were calculated using multivariate logistic regression. A delirium risk score was established as the simple arithmetic sum of points assigned to variables that were significant in the multivariate analyses. Based on the statistical results, the delirium risk score was defined using six factors: old age (≥80 years), hypoalbuminemia, cervical fracture, major organ injury, dependence on pre-injury mobility, and comorbid diabetes. The score’s area under the curve for the prediction of delirium was 0.66 (p < 0.001). Although the current scoring system must be validated with an independent dataset, the system remains beneficial because it can be used after screening examinations upon hospitalization and before deciding the treatment strategy. MDPI 2023-03-20 /pmc/articles/PMC10054626/ /pubmed/36983387 http://dx.doi.org/10.3390/jcm12062387 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Tamai, Koji Terai, Hidetomi Nakamura, Hiroaki Yokogawa, Noriaki Sasagawa, Takeshi Nakashima, Hiroaki Segi, Naoki Ito, Sadayuki Funayama, Toru Eto, Fumihiko Yamaji, Akihiro Watanabe, Kota Yamane, Junichi Takeda, Kazuki Furuya, Takeo Yunde, Atsushi Nakajima, Hideaki Yamada, Tomohiro Hasegawa, Tomohiko Terashima, Yoshinori Hirota, Ryosuke Suzuki, Hidenori Imajo, Yasuaki Ikegami, Shota Uehara, Masashi Tonomura, Hitoshi Sakata, Munehiro Hashimoto, Ko Onoda, Yoshito Kawaguchi, Kenichi Haruta, Yohei Suzuki, Nobuyuki Kato, Kenji Uei, Hiroshi Sawada, Hirokatsu Nakanishi, Kazuo Misaki, Kosuke Kuroda, Akiyoshi Inoue, Gen Kakutani, Kenichiro Kakiuchi, Yuji Kiyasu, Katsuhito Tominaga, Hiroyuki Tokumoto, Hiroto Iizuka, Yoichi Takasawa, Eiji Akeda, Koji Takegami, Norihiko Funao, Haruki Oshima, Yasushi Kaito, Takashi Sakai, Daisuke Yoshii, Toshitaka Ohba, Tetsuro Otsuki, Bungo Seki, Shoji Miyazaki, Masashi Ishihara, Masayuki Okada, Seiji Imagama, Shiro Kato, Satoshi Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture |
title | Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture |
title_full | Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture |
title_fullStr | Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture |
title_full_unstemmed | Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture |
title_short | Delirium Risk Score in Elderly Patients with Cervical Spinal Cord Injury and/or Cervical Fracture |
title_sort | delirium risk score in elderly patients with cervical spinal cord injury and/or cervical fracture |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054626/ https://www.ncbi.nlm.nih.gov/pubmed/36983387 http://dx.doi.org/10.3390/jcm12062387 |
work_keys_str_mv | AT tamaikoji deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT teraihidetomi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT nakamurahiroaki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT yokogawanoriaki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT sasagawatakeshi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT nakashimahiroaki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT seginaoki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT itosadayuki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT funayamatoru deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT etofumihiko deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT yamajiakihiro deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT watanabekota deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT yamanejunichi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT takedakazuki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT furuyatakeo deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT yundeatsushi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT nakajimahideaki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT yamadatomohiro deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT hasegawatomohiko deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT terashimayoshinori deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT hirotaryosuke deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT suzukihidenori deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT imajoyasuaki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT ikegamishota deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT ueharamasashi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT tonomurahitoshi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT sakatamunehiro deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT hashimotoko deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT onodayoshito deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT kawaguchikenichi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT harutayohei deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT suzukinobuyuki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT katokenji deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT ueihiroshi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT sawadahirokatsu deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT nakanishikazuo deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT misakikosuke deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT kurodaakiyoshi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT inouegen deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT kakutanikenichiro deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT kakiuchiyuji deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT kiyasukatsuhito deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT tominagahiroyuki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT tokumotohiroto deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT iizukayoichi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT takasawaeiji deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT akedakoji deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT takegaminorihiko deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT funaoharuki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT oshimayasushi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT kaitotakashi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT sakaidaisuke deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT yoshiitoshitaka deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT ohbatetsuro deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT otsukibungo deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT sekishoji deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT miyazakimasashi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT ishiharamasayuki deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT okadaseiji deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT imagamashiro deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture AT katosatoshi deliriumriskscoreinelderlypatientswithcervicalspinalcordinjuryandorcervicalfracture |