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Molecular Anatomy of the EML4-ALK Fusion Protein for the Development of Novel Anticancer Drugs

The EML4 (echinoderm microtubule-associated protein-like 4)-ALK (anaplastic lymphoma kinase) fusion gene in non-small-cell lung cancer (NSCLC) was first identified in 2007. As the EML4-ALK fusion protein promotes carcinogenesis in lung cells, much attention has been paid to it, leading to the develo...

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Detalles Bibliográficos
Autores principales: Cheon, So Yeong, Kwon, Sunghark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054655/
https://www.ncbi.nlm.nih.gov/pubmed/36982897
http://dx.doi.org/10.3390/ijms24065821