Cargando…

Preparation, Characterization and Evaluation of Flavonolignan Silymarin Effervescent Floating Matrix Tablets for Enhanced Oral Bioavailability

The convenient and highly compliant route for the delivery of active pharmaceutical ingredients is the tablet. A versatile platform of tablets is available for the delivery of therapeutic agents to the gastrointestinal tract. This study aimed to prepare gastro retentive drug delivery floating tablet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahmad, Sher, Khan, Jamshaid Ali, Kausar, Tabassum Naheed, Mahnashi, Mater H., Alasiri, Ali, Alqahtani, Abdulsalam A., Alqahtani, Thamer S., Walbi, Ismail A., Alshehri, Osama M., Elnoubi, Osman A., Mahmood, Fawad, Sadiq, Abdul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054735/ https://www.ncbi.nlm.nih.gov/pubmed/36985575 http://dx.doi.org/10.3390/molecules28062606

Ejemplares similares

Skin Protective Activity of Silymarin and its Flavonolignans
por: Vostálová, Jitka, et al.
Publicado: (2019)

Biotransformation of Silymarin Flavonolignans by Human Fecal Microbiota
por: Valentová, Kateřina, et al.
Publicado: (2020)

Identification of Human Sulfotransferases Active towards Silymarin Flavonolignans and Taxifolin
por: Vrba, Jiří, et al.
Publicado: (2020)

Simple and Rapid HPLC Separation and Quantification of Flavonoid, Flavonolignans, and 2,3-Dehydroflavonolignans in Silymarin
por: Petrásková, Lucie, et al.
Publicado: (2020)

The Effect of Silymarin Flavonolignans and Their Sulfated Conjugates on Platelet Aggregation and Blood Vessels Ex Vivo
por: Pourová, Jana, et al.
Publicado: (2019)

Role of UDP-Glucuronosyltransferase 1A1 in the Metabolism and Pharmacokinetics of Silymarin Flavonolignans in Patients with HCV and NAFLD
por: Xie, Ying, et al.
Publicado: (2017)

Formulation and In Vitro, In Vivo Evaluation of Effervescent Floating Sustained-Release Imatinib Mesylate Tablet
por: Kadivar, Ali, et al.
Publicado: (2015)

Potential Effects of Silymarin and Its Flavonolignan Components in Patients with β-Thalassemia Major: A Comprehensive Review in 2015
por: Darvishi Khezri, Hadi, et al.
Publicado: (2016)

Antidiabetic, Antihyperlipidemic, and Antioxidant Evaluation of Phytosteroids from Notholirion thomsonianum (Royle) Stapf
por: Huneif, Mohammad A., et al.
Publicado: (2023)

Design and evaluation of effervescent floating tablets based on hydroxyethyl cellulose and sodium alginate using pentoxifylline as a model drug
por: Rahim, Safwan Abdel, et al.
Publicado: (2015)

Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic Acids through In Vitro, In Silico and In Vivo Studies
por: Mahmood, Fawad, et al.
Publicado: (2022)

Dose Effect of Milk Thistle (Silybum marianum) Seed Cakes on the Digestibility of Nutrients, Flavonolignans and the Individual Components of the Silymarin Complex in Horses
por: Dockalova, Hana, et al.
Publicado: (2021)

Effect of bioadhesion on initial in vitro buoyancy of effervescent floating matrix tablets of ciprofloxacin HCL
por: Negi, Jeetendra Singh, et al.
Publicado: (2011)

Cytotoxicity, anti-angiogenic, anti-tumor and molecular docking studies on phytochemicals isolated from Polygonum hydropiper L.
por: Mahnashi, Mater H., et al.
Publicado: (2021)

Design and In-vitro Evaluation of Sustained Release Floating Tablets of Metformin HCl Based on Effervescence and Swelling
por: Senjoti, Faria Gias, et al.
Publicado: (2016)

Correction: Formulation and In Vitro, In Vivo Evaluation of Effervescent Floating Sustained-Release Imatinib Mesylate Tablet
Publicado: (2022)

GC-MS Analysis and Various In Vitro and In Vivo Pharmacological Potential of Habenaria plantaginea Lindl.
por: Mahnashi, Mater H., et al.
Publicado: (2022)

Crude extract and isolated bioactive compounds from Notholirion thomsonianum (Royale) Stapf as multitargets antidiabetic agents: in-vitro and molecular docking approaches
por: Mahnashi, Mater H., et al.
Publicado: (2021)

Predicting Hydroxychloroquine Clearance in Healthy and Diseased Populations Using a Physiologically Based Pharmacokinetic Approach
por: Alqahtani, Faleh, et al.
Publicado: (2023)

Effervescing Powders
por: Maisch, Jno. M.
Publicado: (1857)

Effervescent Salts
por: Pickerill, G. W.
Publicado: (1890)

Physicochemical Characterization of Chitosan-Decorated Finasteride Solid Lipid Nanoparticles for Skin Drug Delivery
por: Sohaib, Muhammad, et al.
Publicado: (2022)

Neuroprotective potentials of selected natural edible oils using enzyme inhibitory, kinetic and simulation approaches
por: Mahnashi, Mater H., et al.
Publicado: (2021)

Synthesis of Michael Adducts as Key Building Blocks for Potential Analgesic Drugs: In vitro, in vivo and in silico Explorations
por: Ahmad, Sajjad, et al.
Publicado: (2021)

Juglone from Walnut Produces Cardioprotective Effects against Isoproterenol-Induced Myocardial Injury in SD Rats
por: Ahmad, Taseer, et al.
Publicado: (2022)

Cephalosporin as Potent Urease and Tyrosinase Inhibitor: Exploration through Enzyme Inhibition, Kinetic Mechanism, and Molecular Docking Studies
por: Alqahtani, Yahya S., et al.
Publicado: (2022)

Phytochemistry, anti-diabetic and antioxidant potentials of Allium consanguineum Kunth
por: Mahnashi, Mater H., et al.
Publicado: (2022)

Fused Deposition Modelling 3D-Printed Gastro-Retentive Floating Device for Propranolol Hcl Tablets
por: Alqahtani, Abdulsalam A., et al.
Publicado: (2023)

α-Glucosidase, α-Amylase and Antioxidant Evaluations of Isolated Bioactives from Wild Strawberry
por: Huneif, Mohammed A., et al.
Publicado: (2022)

Antioxidant Molecules Isolated from Edible Prostrate Knotweed: Rational Derivatization to Produce More Potent Molecules
por: Mahnashi, Mater H., et al.
Publicado: (2022)

Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers
por: Gande, S, et al.
Publicado: (2011)

Preparation of Retinoyl-Flavonolignan Hybrids and Their Antioxidant Properties
por: Chambers, Christopher S., et al.
Publicado: (2019)

Selectively Halogenated Flavonolignans—Preparation and Antibacterial Activity
por: Hurtová, Martina, et al.
Publicado: (2022)

Exploration of Succinimide Derivative as a Multi-Target, Anti-Diabetic Agent: In Vitro and In Vivo Approaches
por: Mahnashi, Mater H., et al.
Publicado: (2023)

Recent Progress in Chitosan-Based Nanomedicine for Its Ocular Application in Glaucoma
por: Albarqi, Hassan A., et al.
Publicado: (2023)

An Adoptive Threshold-Based Multi-Level Deep Convolutional Neural Network for Glaucoma Eye Disease Detection and Classification
por: Aamir, Muhammad, et al.
Publicado: (2020)

HPLC-DAD phenolics analysis, α-glucosidase, α-amylase inhibitory, molecular docking and nutritional profiles of Persicaria hydropiper L.
por: Mahnashi, Mater H., et al.
Publicado: (2022)

Synthesis, Molecular Docking Study, and Biological Evaluation of New 4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N’-(2-(substituted)acetyl)benzohydrazides as Dual Enoyl ACP Reductase and DHFR Enzyme Inhibitors
por: Mahnashi, Mater H., et al.
Publicado: (2023)

Design and Evaluation of Losartan Potassium Effervescent Floating Matrix Tablets: In Vivo X-ray Imaging and Pharmacokinetic Studies in Albino Rabbits
por: Rahamathulla, Mohamed, et al.
Publicado: (2021)

Facile fabrication of boron and nitrogen co-doped carbon dots for “ON–OFF–ON” fluorescence sensing of Al(3+) and F(−) ions in water samples
por: Alqahtani, Yahya S., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_o1pe068av0tlkhokbma4jl0lqv