Micro-Scale Vacuum Compression Molding as a Predictive Screening Tool of Protein Integrity for Potential Hot-Melt Extrusion Processes

Hot-melt extrusion (HME) is used for the production of solid protein formulations mainly for two reasons: increased protein stability in solid state and/or long-term release systems (e.g., protein-loaded implants). However, HME requires considerable amounts of material even at small-scale (>2 g b...

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Detalles Bibliográficos
Autores principales: Dauer, Katharina, Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054806/
https://www.ncbi.nlm.nih.gov/pubmed/36986585
http://dx.doi.org/10.3390/pharmaceutics15030723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054806/
https://www.ncbi.nlm.nih.gov/pubmed/36986585
http://dx.doi.org/10.3390/pharmaceutics15030723

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