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Decoding optimal ligand design for multicomponent condensates

Biomolecular condensates form via multivalent interactions among key macromolecules and are regulated through ligand binding and/or post-translational modifications. One such modification is ubiquitination, the covalent addition of ubiquitin (Ub) or polyubiquitin chains to target macromolecules for...

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Detalles Bibliográficos
Autores principales:	Galagedera, Sarasi K. K., Dao, Thuy P., Enos, Suzanne E., Chaudhuri, Antara, Schmit, Jeremy D., Castañeda, Carlos A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054939/ https://www.ncbi.nlm.nih.gov/pubmed/36993708 http://dx.doi.org/10.1101/2023.03.13.532222

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