Cargando…
Voltage-dependent volume regulation controls epithelial cell extrusion and morphology
Epithelial cells work collectively to provide a protective barrier, yet also turn over rapidly by cell death and division. If the number of dying cells does not match those dividing, the barrier would vanish, or tumors can form. Mechanical forces and the stretch-activated ion channel (SAC) Piezo1 li...
Autores principales: | Mitchell, Saranne J., Pardo-Pastor, Carlos, Zangle, Thomas A., Rosenblatt, Jody |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054995/ https://www.ncbi.nlm.nih.gov/pubmed/36993671 http://dx.doi.org/10.1101/2023.03.13.532421 |
Ejemplares similares
-
Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway
por: Gu, Yapeng, et al.
Publicado: (2011) -
The role of tissue maturity and mechanical state in controlling cell extrusion
por: Zulueta-Coarasa, Teresa, et al.
Publicado: (2022) -
Piezo1 activates noncanonical EGFR endocytosis and signaling
por: Pardo-Pastor, Carlos, et al.
Publicado: (2023) -
Defective apical extrusion signaling contributes to aggressive tumor hallmarks
por: Gu, Yapeng, et al.
Publicado: (2015) -
Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia
por: Eisenhoffer, George T., et al.
Publicado: (2012)