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An alphacoronavirus polymerase structure reveals conserved co-factor functions
Coronaviruses are a diverse subfamily of viruses containing pathogens of humans and animals. This subfamily of viruses replicates their RNA genomes using a core polymerase complex composed of viral non-structural proteins: nsp7, nsp8 and nsp12. Most of our understanding of coronavirus molecular biol...
Autores principales: | Anderson, Thomas K., Hoferle, Peter J., Lee, Kenneth W., Coon, Joshua J., Kirchdoerfer, Robert N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055115/ https://www.ncbi.nlm.nih.gov/pubmed/36993498 http://dx.doi.org/10.1101/2023.03.15.532841 |
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