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An alphacoronavirus polymerase structure reveals conserved co-factor functions

Coronaviruses are a diverse subfamily of viruses containing pathogens of humans and animals. This subfamily of viruses replicates their RNA genomes using a core polymerase complex composed of viral non-structural proteins: nsp7, nsp8 and nsp12. Most of our understanding of coronavirus molecular biol...

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Detalles Bibliográficos
Autores principales: Anderson, Thomas K., Hoferle, Peter J., Lee, Kenneth W., Coon, Joshua J., Kirchdoerfer, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055115/
https://www.ncbi.nlm.nih.gov/pubmed/36993498
http://dx.doi.org/10.1101/2023.03.15.532841

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