Hem25p is a mitochondrial IPP transporter

Coenzyme Q (CoQ, ubiquinone) is an essential cellular cofactor comprised of a redox-active quinone head group and a long hydrophobic polyisoprene tail. How mitochondria access cytosolic isoprenoids for CoQ biosynthesis is a longstanding mystery. Here, via a combination of genetic screening, metaboli...

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Detalles Bibliográficos
Autores principales: Tai, Jonathan, Guerra, Rachel M., Rogers, Sean W., Fang, Zixiang, Muehlbauer, Laura K., Shishkova, Evgenia, Overmyer, Katherine A., Coon, Joshua J., Pagliarini, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055127/
https://www.ncbi.nlm.nih.gov/pubmed/36993473
http://dx.doi.org/10.1101/2023.03.14.532620

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