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A paradox promoted by microglia cannibalism shortens the lifespan of developmental microglia

The overproduction of cells and subsequent production of debris is a universal principle of neurodevelopment. Here we show an additional feature of the developing nervous system that causes neural debris – promoted by the sacrificial nature of embryonic microglia that irreversibly become phagocytic...

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Detalles Bibliográficos
Autores principales: Gordon, Hannah, Schafer, Zachary T., Smith, Cody J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055159/
https://www.ncbi.nlm.nih.gov/pubmed/36993267
http://dx.doi.org/10.1101/2023.03.15.532426