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A paradox promoted by microglia cannibalism shortens the lifespan of developmental microglia
The overproduction of cells and subsequent production of debris is a universal principle of neurodevelopment. Here we show an additional feature of the developing nervous system that causes neural debris – promoted by the sacrificial nature of embryonic microglia that irreversibly become phagocytic...
Autores principales: | Gordon, Hannah, Schafer, Zachary T., Smith, Cody J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055159/ https://www.ncbi.nlm.nih.gov/pubmed/36993267 http://dx.doi.org/10.1101/2023.03.15.532426 |
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