Phosphorylation barcodes direct biased chemokine signaling at CXCR3

G protein-coupled receptor (GPCR) biased agonism, the activation of some signaling pathways over others, is thought to largely be due to differential receptor phosphorylation, or “phosphorylation barcodes.” At chemokine receptors, ligands act as “biased agonists” with complex signaling profiles, whi...

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Detalles Bibliográficos
Autores principales: Eiger, Dylan S., Smith, Jeffrey S., Shi, Tujin, Stepniewski, Tomasz Maciej, Tsai, Chia-Feng, Honeycutt, Christopher, Boldizsar, Noelia, Gardner, Julia, Nicora, Carrie D., Moghieb, Ahmed M., Kawakami, Kouki, Choi, Issac, Zheng, Kevin, Warman, Anmol, Alagesan, Priya, Knape, Nicole M., Huang, Ouwen, Silverman, Justin D., Smith, Richard D., Inoue, Asuka, Selent, Jana, Jacobs, Jon M., Rajagopal, Sudarshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055163/
https://www.ncbi.nlm.nih.gov/pubmed/36993369
http://dx.doi.org/10.1101/2023.03.14.532634

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