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Mechanisms of transcription control by distal enhancers from high-resolution single-gene imaging

How distal enhancers physically control promoters over large genomic distances, to enable cell-type specific gene expression, remains obscure. Using single-gene super-resolution imaging and acute targeted perturbations, we define physical parameters of enhancer-promoter communication and elucidate p...

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Detalles Bibliográficos
Autores principales:	Cheng, Lingling, De, Chayan, Li, Jieru, Pertsinidis, Alexandros
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055225/ https://www.ncbi.nlm.nih.gov/pubmed/36993179 http://dx.doi.org/10.1101/2023.03.19.533190

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