Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer

To identify novel drivers of malignancy in pancreatic ductal adenocarcinoma (PDAC), we employed regulatory network analysis, which calculates the activity of transcription factors and other regulatory proteins based on the integrated expression of their positive and negative target genes. We generat...

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Detalles Bibliográficos
Autores principales: Maurer, H. Carlo, Curiel-Garcia, Alvaro, Holmstrom, Sam, Laise, Pasquale, Palermo, Carmine F., Sastra, Steven A., Andren, Anthony, Li, Zhang, LeLarge, Tessa, Sagalovskiy, Irina, Ross, Daniel R., Rosario, Vilma, Lu, Kate, Ferraiuolo, Ethan, Spinosa, Nicholas, Wong, Winston, Shaw, Kaitlin, Chabot, John A., Genkinger, Jeanine, Hibshoosh, Hanina, Manji, Gulam A., Iuga, Alina, Schmid, Roland M., Badgley, Michael A., Johnson, Kristen, Califano, Andrea, Lyssiotis, Costas, Olive, Kenneth P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055246/
https://www.ncbi.nlm.nih.gov/pubmed/36993718
http://dx.doi.org/10.1101/2023.03.19.533333

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