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Gata3 is detrimental to regulatory T cell function in autoimmune diabetes

Regulatory T cells (Tregs) protect against autoimmunity. In type 1 diabetes (T1D), Tregs slow the progression of beta cell autoimmunity within pancreatic islets. Increasing the potency or frequency of Tregs can prevent diabetes, as evidenced by studies in the nonobese diabetic (NOD) mouse model for...

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Detalles Bibliográficos
Autores principales: Kiaf, Badr, Bode, Kevin, Schuster, Cornelia, Kissler, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055278/
https://www.ncbi.nlm.nih.gov/pubmed/36993342
http://dx.doi.org/10.1101/2023.03.18.533297

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