Bacterial genome engineering using CRISPR RNA-guided transposases

CRISPR-associated transposons (CASTs) have the potential to transform the technology landscape for kilobase-scale genome engineering, by virtue of their ability to integrate large genetic payloads with high accuracy, easy programmability, and no requirement for homologous recombination machinery. Th...

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Detalles Bibliográficos
Autores principales: Gelsinger, Diego R., Vo, Phuc Leo H., Klompe, Sanne E., Ronda, Carlotta, Wang, Harris, Sternberg, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055292/
https://www.ncbi.nlm.nih.gov/pubmed/36993567
http://dx.doi.org/10.1101/2023.03.18.533263

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