Elevated CD153 Expression on Aged T Follicular Helper Cells is Vital for B cell Responses

Our recent data showed that an aberrant IL-10-producing T follicular helper population (Tfh10) accumulates dramatically with age and is associated with age-related declines in vaccine responsiveness. Through single cell gene expression and chromatin accessibility analysis of IL-10(+) and IL-10(−) me...

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Detalles Bibliográficos
Autores principales: Thomas, Alyssa L., Wayman, Joseph A., Almanan, Maha, Bejjani, Anthony T., Miraldi, Emily R., Chougnet, Claire A., Hildeman, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055293/
https://www.ncbi.nlm.nih.gov/pubmed/36993647
http://dx.doi.org/10.1101/2023.03.17.533214

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