TREM2 and APOE do not modulate phagocytic clearance of dying cells in the live mammalian brain

TREM2 and APOE are two major risk factors for Alzheimer’s disease (AD) that have been proposed to play crucial roles in microglia pathophysiology by affecting their ability to phagocytose cellular debris or aggregated proteins. In this study, we investigated for the first time the impact of TREM2 an...

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Detalles Bibliográficos
Autores principales: Damisah, Eyiyemisi C., Rai, Anupama, Hill, Robert A., Tong, Lei, Grutzendler, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055304/
https://www.ncbi.nlm.nih.gov/pubmed/36993245
http://dx.doi.org/10.1101/2023.03.17.533222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055304/
https://www.ncbi.nlm.nih.gov/pubmed/36993245
http://dx.doi.org/10.1101/2023.03.17.533222

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