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TREM2 and APOE do not modulate phagocytic clearance of dying cells in the live mammalian brain
TREM2 and APOE are two major risk factors for Alzheimer’s disease (AD) that have been proposed to play crucial roles in microglia pathophysiology by affecting their ability to phagocytose cellular debris or aggregated proteins. In this study, we investigated for the first time the impact of TREM2 an...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055304/ https://www.ncbi.nlm.nih.gov/pubmed/36993245 http://dx.doi.org/10.1101/2023.03.17.533222 |