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Inferring CpG methylation signatures accumulated along human history from genetic variation catalogs
Understanding the DNA methylation patterns in the human genome is a key step to decipher gene regulatory mechanisms and model mutation rate heterogeneity in the human genome. While methylation rates can be measured e.g. with bisulfite sequencing, such measures do not capture historical patterns. Her...
Autores principales: | Si, Yichen, Zöllner, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055312/ https://www.ncbi.nlm.nih.gov/pubmed/36993375 http://dx.doi.org/10.1101/2023.03.24.534151 |
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