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Inferring CpG methylation signatures accumulated along human history from genetic variation catalogs

Understanding the DNA methylation patterns in the human genome is a key step to decipher gene regulatory mechanisms and model mutation rate heterogeneity in the human genome. While methylation rates can be measured e.g. with bisulfite sequencing, such measures do not capture historical patterns. Her...

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Detalles Bibliográficos
Autores principales: Si, Yichen, Zöllner, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055312/
https://www.ncbi.nlm.nih.gov/pubmed/36993375
http://dx.doi.org/10.1101/2023.03.24.534151

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