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Beyond the reference: gene expression variation and transcriptional response to RNAi in C. elegans

A universal feature of living systems is that natural variation in genotype underpins variation in phenotype. Yet, research in model organisms is often constrained to a single genetic background, the reference strain. Further, genomic studies that do evaluate wild strains typically rely on the refer...

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Detalles Bibliográficos
Autores principales: Bell, Avery Davis, Chou, Han Ting, Paaby, Annalise B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055391/
https://www.ncbi.nlm.nih.gov/pubmed/36993640
http://dx.doi.org/10.1101/2023.03.24.533964