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Role of Lactate in the Regulation of Transcriptional Activity of Breast Cancer-Related Genes and Epithelial-to-Mesenchymal Transition Proteins: A Compassion of MCF7 and MDA-MB-231 Cancer Cell Lines

The Warburg Effect is characterized by accelerated glycolytic metabolism and lactate production and under fully aerobic conditions is a hallmark of cancer cells. Recently, we have demonstrated the role of endogenous, glucose-derived lactate as an oncometabolite which regulates gene expression in the...

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Detalles Bibliográficos
Autores principales:	San-Millan, Inigo, Martinez, Janel L., Pickard, Shivaun Lueke, Yu, Hui, Hirsch, Fred R., Rivard, Christopher J., Brooks, George A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055400/ https://www.ncbi.nlm.nih.gov/pubmed/36993762 http://dx.doi.org/10.1101/2023.03.23.533060

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