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Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model

Despite widespread immunization with Bacille-Calmette-Guerin (BCG), the only currently licensed tuberculosis (TB) vaccine, TB remains a leading cause of mortality globally. There are many TB vaccine candidates in the developmental pipeline, but the lack of a robust animal model to assess vaccine eff...

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Detalles Bibliográficos
Autores principales: Plumlee, C.R., Barrett, H.W., Shao, D.E., Lien, K.A., Cross, L.M., Cohen, S.B., Edlefsen, P.T, Urdahl, K.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055404/
https://www.ncbi.nlm.nih.gov/pubmed/36993415
http://dx.doi.org/10.1101/2023.03.22.533820