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Endothelial Cell SMAD6 Balances ACVRL1/Alk1 Function to Regulate Adherens Junctions and Hepatic Vascular Development

BMP signaling is critical to blood vessel formation and function, but how pathway components regulate vascular development is not well-understood. Here we find that inhibitory SMAD6 functions in endothelial cells to negatively regulate ALK1/ACVRL1-mediated responses, and it is required to prevent ve...

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Detalles Bibliográficos
Autores principales:	Kulikauskas, Molly R, Oatley, Morgan, Yu, Tianji, Liu, Ziqing, Matsumura, Lauren, Kidder, Elise, Ruter, Dana, Bautch, Victoria L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055411/ https://www.ncbi.nlm.nih.gov/pubmed/36993438 http://dx.doi.org/10.1101/2023.03.23.534007

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