Antiviral activities of two nucleos(t)ide analogs against vaccinia and mpox viruses in primary human fibroblasts

Many poxviruses are significant human and animal pathogens, including viruses that cause smallpox and mpox. Identification of inhibitors of poxvirus replication is critical for drug development to manage poxvirus threats. Here we tested two compounds, nucleoside trifluridine and nucleotide adefovir...

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Detalles Bibliográficos
Autores principales: Dsouza, Lara, Pant, Anil, Offei, Samuel, Priyamvada, Lalita, Pope, Blake, Satheshkumar, Panayampalli S., Wang, Zhengqiang, Yang, Zhilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055413/
https://www.ncbi.nlm.nih.gov/pubmed/36993701
http://dx.doi.org/10.1101/2023.03.23.533943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055413/
https://www.ncbi.nlm.nih.gov/pubmed/36993701
http://dx.doi.org/10.1101/2023.03.23.533943

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