Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin

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We and others have previously shown that genetic association can be used to make causal connections between gene loci and small molecules measured by mass spectrometry in the bloodstream and in tissues. We identified a locus on mouse chromosome 7 where several phospholipids in liver showed strong ge...

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Detalles Bibliográficos
Autores principales: Price, Tara R., Stapleton, Donnie S., Schueler, Kathryn L., Norris, Marie K., Parks, Brian W., Yandell, Brian S., Churchill, Gary A., Holland, William L., Keller, Mark P., Attie, Alan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055419/
https://www.ncbi.nlm.nih.gov/pubmed/36993241
http://dx.doi.org/10.1101/2023.03.23.533902
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