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VMAP: Vaginal Microbiome Atlas During Pregnancy
The vaginal microbiome has been shown to be associated with pregnancy outcomes including preterm birth (PTB) risk. Here we present VMAP: Vaginal Microbiome Atlas during Pregnancy (http://vmapapp.org), an application to visualize features of 3,909 vaginal microbiome samples of 1,416 pregnant individu...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055588/ https://www.ncbi.nlm.nih.gov/pubmed/36993193 http://dx.doi.org/10.1101/2023.03.21.23286947 |
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author | Parraga-Leo, Antonio Oskotsky, Tomiko T. Oskotsky, Boris Wibrand, Camilla Roldan, Alennie Tang, Alice Ha, Connie W.Y. Wong, Ronald J. Minot, Samuel S. Andreoletti, Gaia Kosti, Idit Theis, Kevin R. Ng, Sherrianne Lee, Yun S. Diaz-Gimeno, Patricia Bennett, Phillip R. MacIntyre, David A. Lynch, Susan V. Romero, Roberto Tarca, Adi L. Stevenson, David K. Aghaeepour, Nima Golob, Jonathan Sirota, Marina |
author_facet | Parraga-Leo, Antonio Oskotsky, Tomiko T. Oskotsky, Boris Wibrand, Camilla Roldan, Alennie Tang, Alice Ha, Connie W.Y. Wong, Ronald J. Minot, Samuel S. Andreoletti, Gaia Kosti, Idit Theis, Kevin R. Ng, Sherrianne Lee, Yun S. Diaz-Gimeno, Patricia Bennett, Phillip R. MacIntyre, David A. Lynch, Susan V. Romero, Roberto Tarca, Adi L. Stevenson, David K. Aghaeepour, Nima Golob, Jonathan Sirota, Marina |
author_sort | Parraga-Leo, Antonio |
collection | PubMed |
description | The vaginal microbiome has been shown to be associated with pregnancy outcomes including preterm birth (PTB) risk. Here we present VMAP: Vaginal Microbiome Atlas during Pregnancy (http://vmapapp.org), an application to visualize features of 3,909 vaginal microbiome samples of 1,416 pregnant individuals from 11 studies, aggregated from raw public and newly generated sequences via an open-source tool, MaLiAmPi. Our visualization tool (http://vmapapp.org) includes microbial features such as various measures of diversity, VALENCIA community state types (CST), and composition (via phylotypes and taxonomy). This work serves as a resource for the research community to further analyze and visualize vaginal microbiome data in order to better understand both healthy term pregnancies and those associated with adverse outcomes. |
format | Online Article Text |
id | pubmed-10055588 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cold Spring Harbor Laboratory |
record_format | MEDLINE/PubMed |
spelling | pubmed-100555882023-03-30 VMAP: Vaginal Microbiome Atlas During Pregnancy Parraga-Leo, Antonio Oskotsky, Tomiko T. Oskotsky, Boris Wibrand, Camilla Roldan, Alennie Tang, Alice Ha, Connie W.Y. Wong, Ronald J. Minot, Samuel S. Andreoletti, Gaia Kosti, Idit Theis, Kevin R. Ng, Sherrianne Lee, Yun S. Diaz-Gimeno, Patricia Bennett, Phillip R. MacIntyre, David A. Lynch, Susan V. Romero, Roberto Tarca, Adi L. Stevenson, David K. Aghaeepour, Nima Golob, Jonathan Sirota, Marina medRxiv Article The vaginal microbiome has been shown to be associated with pregnancy outcomes including preterm birth (PTB) risk. Here we present VMAP: Vaginal Microbiome Atlas during Pregnancy (http://vmapapp.org), an application to visualize features of 3,909 vaginal microbiome samples of 1,416 pregnant individuals from 11 studies, aggregated from raw public and newly generated sequences via an open-source tool, MaLiAmPi. Our visualization tool (http://vmapapp.org) includes microbial features such as various measures of diversity, VALENCIA community state types (CST), and composition (via phylotypes and taxonomy). This work serves as a resource for the research community to further analyze and visualize vaginal microbiome data in order to better understand both healthy term pregnancies and those associated with adverse outcomes. Cold Spring Harbor Laboratory 2023-04-05 /pmc/articles/PMC10055588/ /pubmed/36993193 http://dx.doi.org/10.1101/2023.03.21.23286947 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which allows reusers to copy and distribute the material in any medium or format in unadapted form only, for noncommercial purposes only, and only so long as attribution is given to the creator. |
spellingShingle | Article Parraga-Leo, Antonio Oskotsky, Tomiko T. Oskotsky, Boris Wibrand, Camilla Roldan, Alennie Tang, Alice Ha, Connie W.Y. Wong, Ronald J. Minot, Samuel S. Andreoletti, Gaia Kosti, Idit Theis, Kevin R. Ng, Sherrianne Lee, Yun S. Diaz-Gimeno, Patricia Bennett, Phillip R. MacIntyre, David A. Lynch, Susan V. Romero, Roberto Tarca, Adi L. Stevenson, David K. Aghaeepour, Nima Golob, Jonathan Sirota, Marina VMAP: Vaginal Microbiome Atlas During Pregnancy |
title | VMAP: Vaginal Microbiome Atlas During Pregnancy |
title_full | VMAP: Vaginal Microbiome Atlas During Pregnancy |
title_fullStr | VMAP: Vaginal Microbiome Atlas During Pregnancy |
title_full_unstemmed | VMAP: Vaginal Microbiome Atlas During Pregnancy |
title_short | VMAP: Vaginal Microbiome Atlas During Pregnancy |
title_sort | vmap: vaginal microbiome atlas during pregnancy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055588/ https://www.ncbi.nlm.nih.gov/pubmed/36993193 http://dx.doi.org/10.1101/2023.03.21.23286947 |
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