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Non-additive effects of schizophrenia risk genes reflect convergent downstream function

Genetic studies of schizophrenia (SCZ) reveal a complex polygenic risk architecture comprised of hundreds of risk variants, the majority of which are common in the population at-large and confer only modest increases in disorder risk. Precisely how genetic variants with individually small predicted...

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Detalles Bibliográficos
Autores principales:	Deans, PJ Michael, Seah, Carina, Johnson, Jessica, Gonzalez, Judit Garcia, Townsley, Kayla, Cao, Evan, Schrode, Nadine, Stahl, Eli, O’Reilly, Paul, Huckins, Laura M., Brennand, Kristen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055596/ https://www.ncbi.nlm.nih.gov/pubmed/36993466 http://dx.doi.org/10.1101/2023.03.20.23287497

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