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Augmentation of Pectoral Fin Teratogenicity by Thalidomide in Human Cytochrome P450 3A-Expressing Zebrafish

The pharmacological and toxicological effects of active metabolites of enzymes including cytochrome P450 (CYP) are important. While it has been believed for a long time that thalidomide causes characteristic limb malformation only in rabbits and primates including humans, the involvement of their CY...

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Detalles Bibliográficos
Autores principales:	Dong, Wenjing, Akasaka, Ippo, Komiyama, Akifumi, Nakamura, Tatsuro, Mizoguchi, Naohiro, Nawaji, Tasuku, Ikushiro, Shinichi, Kobayashi, Makoto, Teraoka, Hiroki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055635/ https://www.ncbi.nlm.nih.gov/pubmed/36986467 http://dx.doi.org/10.3390/ph16030368

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