Evolution of promoter-proximal pausing enabled a new layer of transcription control

Promoter-proximal pausing of RNA polymerase II (Pol II) is a key regulatory step during transcription. Despite the central role of pausing in gene regulation, we do not understand the evolutionary processes that led to the emergence of Pol II pausing or its transition to a rate-limiting step activel...

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Detalles Bibliográficos
Autores principales: Chivu, Alexandra G., Abuhashem, Abderhman, Barshad, Gilad, Rice, Edward J., Leger, Michelle M., Vill, Albert C., Wong, Wilfred, Brady, Rebecca, Smith, Jeramiah J., Wikramanayake, Athula H., Arenas-Mena, César, Brito, Ilana L., Ruiz-Trillo, Iñaki, Hadjantonakis, Anna-Katerina, Lis, John T., Lewis, James J., Danko, Charles G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055653/
https://www.ncbi.nlm.nih.gov/pubmed/36993251
http://dx.doi.org/10.21203/rs.3.rs-2679520/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055653/
https://www.ncbi.nlm.nih.gov/pubmed/36993251
http://dx.doi.org/10.21203/rs.3.rs-2679520/v1

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