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Single cell and spatial alternative splicing analysis with long read sequencing

Long-read sequencing has become a powerful tool for alternative splicing analysis. However, technical and computational challenges have limited our ability to explore alternative splicing at single cell and spatial resolution. The higher sequencing error of long reads, especially high indel rates, h...

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Detalles Bibliográficos
Autores principales: Fu, Yuntian, Kim, Heonseok, Adams, Jenea I., Grimes, Susan M., Huang, Sijia, Lau, Billy T., Sathe, Anuja, Hess, Paul, Ji, Hanlee P., Zhang, Nancy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055662/
https://www.ncbi.nlm.nih.gov/pubmed/36993612
http://dx.doi.org/10.21203/rs.3.rs-2674892/v1