Cargando…

Synthesis of 5,6-Dihydrophenanthridines via Palladium-Catalyzed Intramolecular Dehydrogenative Coupling of Two Aryl C−H Bonds

5,6-Dihydrophenanthridines are common aza heterocycle frameworks of natural products and pharmaceuticals. Herein, we reported the first palladium-catalyzed intramolecular C−H/C−H dehydrogenative coupling reaction of two simple arenes to generate 5,6-dihydrophenanthridines. The approach features a br...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Meng-Yue, Zhu, Xue-Qing, Zhao, Bao-Yin, Zhang, Hong-Xia, Wang, Yong-Qiang, Jia, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055664/ https://www.ncbi.nlm.nih.gov/pubmed/36985470 http://dx.doi.org/10.3390/molecules28062498

Ejemplares similares

Synthesis of dihydrophenanthridines by a sequence of Ugi-4CR and palladium-catalyzed intramolecular C-H functionalization
por: Bonnaterre, Florence, et al.
Publicado: (2008)

Palladium-Catalyzed Intramolecular Oxidative Arylations for the Synthesis of Fused Biaryl Sulfones
por: Laha, Joydev K., et al.
Publicado: (2018)

Streamlined construction of peptide macrocycles via palladium-catalyzed intramolecular S-arylation in solution and on DNA
por: Yang, Peng, et al.
Publicado: (2021)

Palladium-Catalyzed Intramolecular Cross-Dehydrogenative Coupling: Synthesis of Fused Imidazo[1,2-a]pyrimidines and Pyrazolo[1,5-a]pyrimidines
por: Reddy Kotla, Siva K., et al.
Publicado: (2017)

Stereoselective synthesis of tricyclic compounds by intramolecular palladium-catalyzed addition of aryl iodides to carbonyl groups
por: Saadi, Jakub, et al.
Publicado: (2016)

Nickel catalyzed intramolecular oxidative coupling: synthesis of 3-aryl benzofurans
por: Aggarwal, Sakshi, et al.
Publicado: (2020)

Palladium-Catalyzed Dehydrogenative Coupling: An Efficient Synthetic Strategy for the Construction of the Quinoline Core
por: Carral-Menoyo, Asier, et al.
Publicado: (2017)

Palladium-catalyzed dehydrogenative C–H cyclization for isoindolinone synthesis
por: Abe, Masahiro, et al.
Publicado: (2021)

Synthesis of C(2)-Symmetric Benzimidazolium Salts and Their Application in Palladium-Catalyzed Enantioselective Intramolecular α-Arylation of Amides
por: He, Weiping, et al.
Publicado: (2016)

Palladium-Catalyzed α-Arylation of Aryl Nitromethanes
por: VanGelder, Kelsey F., et al.
Publicado: (2015)

Unified synthesis of mono/bis-arylated phenols via Rh(III)-catalyzed dehydrogenative coupling
por: Wu, Qian, et al.
Publicado: (2017)

Copper-catalyzed diastereoselective aerobic intramolecular dehydrogenative coupling of hydrazones via sp(3) C–H functionalization
por: Wu, Xuesong, et al.
Publicado: (2015)

Copper-catalyzed intramolecular cross dehydrogenative coupling approach to coumestans from 2′-hydroxyl-3-arylcoumarins
por: Song, Xianheng, et al.
Publicado: (2019)

Palladium-Catalyzed Decarboxylative Coupling of Alkynyl Carboxylic Acids with Aryl Tosylates
por: Lee, Ju-Hyeon, et al.
Publicado: (2017)

Synthesis of Fluorinated Alkyl Aryl Ethers by Palladium-Catalyzed C–O Cross-Coupling
por: Szpera, Robert, et al.
Publicado: (2020)

Palladium-catalyzed intramolecular C–H arylation of 2-halo-N-Boc-N-arylbenzamides for the synthesis of N–H phenanthridinones
por: Hu, Quan-Fang, et al.
Publicado: (2018)

Palladium-catalyzed intramolecular Heck dearomative gem-difluorovinylation of indoles
por: Wang, Gang, et al.
Publicado: (2022)

Synthesis of Pyridine-Fused Siloles by Palladium-Catalyzed Intramolecular Bis-Silylation
por: Naka, Akinobu, et al.
Publicado: (2022)

Synthesis of (E,E)-Dienones and (E,E)-Dienals via Palladium-Catalyzed γ,δ-Dehydrogenation of Enones and Enals
por: Pan, Gao-Fei, et al.
Publicado: (2019)

Nickel‐Catalyzed Inter‐ and Intramolecular Aryl Thioether Metathesis by Reversible Arylation
por: Delcaillau, Tristan, et al.
Publicado: (2019)

Palladium-catalyzed intramolecular asymmetric hydrocyclopropanylation of alkynes: synthesis of cyclopropane-fused γ-lactams
por: Lin, Han-Ze, et al.
Publicado: (2023)

Palladium-Catalyzed C–P Bond-Forming Reactions of Aryl Nonaflates Accelerated by Iodide
por: McErlain, Holly, et al.
Publicado: (2021)

Enantioselective Carbocycle Formation through Intramolecular Pd-Catalyzed Allyl–Aryl Cross-Coupling
por: Schuster, Christopher H., et al.
Publicado: (2014)

Mechanistic Studies of the Palladium-Catalyzed Desulfinative Cross-Coupling of Aryl Bromides and (Hetero)Aryl Sulfinate Salts
por: de Gombert, Antoine, et al.
Publicado: (2020)

Microwave-assisted synthesis of 5,6-dihydroindolo[1,2-a]quinoxaline derivatives through copper-catalyzed intramolecular N-arylation
por: Zhao, Fei, et al.
Publicado: (2013)

Palladium-catalyzed intermolecular transthioetherification of aryl halides with thioethers and thioesters
por: Li, Yahui, et al.
Publicado: (2020)

Palladium-Catalyzed α-Arylation of Benzylic Phosphonates
por: Montel, Sonia, et al.
Publicado: (2014)

Reactivity of bromoselenophenes in palladium-catalyzed direct arylations
por: Skhiri, Aymen, et al.
Publicado: (2017)

Palladium-Catalyzed Regioselective Arylation of Unprotected Allylamines
por: Landge, Vinod G., et al.
Publicado: (2020)

Synthesis of benzannelated sultams by intramolecular Pd-catalyzed arylation of tertiary sulfonamides
por: Rassadin, Valentin A, et al.
Publicado: (2017)

Efficient Cu-catalyzed intramolecular O-arylation for synthesis of benzoxazoles in water
por: Tang, Yanling, et al.
Publicado: (2020)

Efficient Palladium-Catalyzed Synthesis of 2-Aryl Propionic Acids
por: Neumann, Helfried, et al.
Publicado: (2020)

Iron-catalyzed α-C–H functionalization of π-bonds: cross-dehydrogenative coupling and mechanistic insights
por: Wang, Yidong, et al.
Publicado: (2020)

Palladium-catalyzed cross-coupling of α-bromocarbonyls and allylic alcohols for the synthesis of α-aryl dicarbonyl compounds
por: Yu, Yang, et al.
Publicado: (2015)

Palladium-catalyzed synthesis of 4-sila-4H-benzo[d][1,3]oxazines by intramolecular Hiyama coupling
por: Lee, Donghyeon, et al.
Publicado: (2023)

Pyridine sulfinates as general nucleophilic coupling partners in palladium-catalyzed cross-coupling reactions with aryl halides
por: Markovic, Tim, et al.
Publicado: (2017)

Iron-catalyzed urea synthesis: dehydrogenative coupling of methanol and amines
por: Lane, Elizabeth M., et al.
Publicado: (2018)

Palladium Catalyzed Heck Arylation of 2,3-Dihydrofuran—Effect of the Palladium Precursor
por: Morel, Adam, et al.
Publicado: (2014)

Palladium-Catalyzed Oxidative Domino Carbocyclization–Arylation of Bisallenes
por: Volla, Chandra M. R., et al.
Publicado: (2016)

Efficient Palladium‐Catalyzed Aerobic Arylative Carbocyclization of Enallenynes
por: Liu, Jie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8cjrtg3r96d0deg3b7oc7257ft