Programmed Death-Ligand 1-Positive Squamous Cell Carcinoma Spontaneously Regressed after Percutaneous Needle Biopsy

Spontaneous lung cancer regression is a very rare course of disease. A 60-year-old male patient was admitted to our hospital with pneumonia and a 19 mm-sized nodule shadow in the S4 of the left lung on chest computed tomography (CT). A percutaneous needle biopsy was performed, and a diagnosis of pro...

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Autores principales: Sasahara, Masayuki, Takahashi, Hiroki, Ohchi, Takashi, Nomura, Naohiro, Kodama, Kentaro, Ikeda, Kimiyuki, Nishikiori, Hirotaka, Okamoto, Kenzo, Chiba, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055785/
https://www.ncbi.nlm.nih.gov/pubmed/36984632
http://dx.doi.org/10.3390/medicina59030631
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author Sasahara, Masayuki
Takahashi, Hiroki
Ohchi, Takashi
Nomura, Naohiro
Kodama, Kentaro
Ikeda, Kimiyuki
Nishikiori, Hirotaka
Okamoto, Kenzo
Chiba, Hirofumi
author_facet Sasahara, Masayuki
Takahashi, Hiroki
Ohchi, Takashi
Nomura, Naohiro
Kodama, Kentaro
Ikeda, Kimiyuki
Nishikiori, Hirotaka
Okamoto, Kenzo
Chiba, Hirofumi
author_sort Sasahara, Masayuki
collection PubMed
description Spontaneous lung cancer regression is a very rare course of disease. A 60-year-old male patient was admitted to our hospital with pneumonia and a 19 mm-sized nodule shadow in the S4 of the left lung on chest computed tomography (CT). A percutaneous needle biopsy was performed, and a diagnosis of programmed death-ligand 1-positive squamous cell lung carcinoma was made based on pathological findings. The patient was followed up with imaging because the lesion has reduced in size on chest CT. We report the possibility that cellular immune mechanisms triggered by needle biopsy contributed to spontaneous regression.
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spelling pubmed-100557852023-03-30 Programmed Death-Ligand 1-Positive Squamous Cell Carcinoma Spontaneously Regressed after Percutaneous Needle Biopsy Sasahara, Masayuki Takahashi, Hiroki Ohchi, Takashi Nomura, Naohiro Kodama, Kentaro Ikeda, Kimiyuki Nishikiori, Hirotaka Okamoto, Kenzo Chiba, Hirofumi Medicina (Kaunas) Case Report Spontaneous lung cancer regression is a very rare course of disease. A 60-year-old male patient was admitted to our hospital with pneumonia and a 19 mm-sized nodule shadow in the S4 of the left lung on chest computed tomography (CT). A percutaneous needle biopsy was performed, and a diagnosis of programmed death-ligand 1-positive squamous cell lung carcinoma was made based on pathological findings. The patient was followed up with imaging because the lesion has reduced in size on chest CT. We report the possibility that cellular immune mechanisms triggered by needle biopsy contributed to spontaneous regression. MDPI 2023-03-22 /pmc/articles/PMC10055785/ /pubmed/36984632 http://dx.doi.org/10.3390/medicina59030631 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Sasahara, Masayuki
Takahashi, Hiroki
Ohchi, Takashi
Nomura, Naohiro
Kodama, Kentaro
Ikeda, Kimiyuki
Nishikiori, Hirotaka
Okamoto, Kenzo
Chiba, Hirofumi
Programmed Death-Ligand 1-Positive Squamous Cell Carcinoma Spontaneously Regressed after Percutaneous Needle Biopsy
title Programmed Death-Ligand 1-Positive Squamous Cell Carcinoma Spontaneously Regressed after Percutaneous Needle Biopsy
title_full Programmed Death-Ligand 1-Positive Squamous Cell Carcinoma Spontaneously Regressed after Percutaneous Needle Biopsy
title_fullStr Programmed Death-Ligand 1-Positive Squamous Cell Carcinoma Spontaneously Regressed after Percutaneous Needle Biopsy
title_full_unstemmed Programmed Death-Ligand 1-Positive Squamous Cell Carcinoma Spontaneously Regressed after Percutaneous Needle Biopsy
title_short Programmed Death-Ligand 1-Positive Squamous Cell Carcinoma Spontaneously Regressed after Percutaneous Needle Biopsy
title_sort programmed death-ligand 1-positive squamous cell carcinoma spontaneously regressed after percutaneous needle biopsy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055785/
https://www.ncbi.nlm.nih.gov/pubmed/36984632
http://dx.doi.org/10.3390/medicina59030631
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