Cannabimimetic N-Stearoylethanolamine as “Double-Edged Sword” in Anticancer Chemotherapy: Proapoptotic Effect on Tumor Cells and Suppression of Tumor Growth versus Its Bio-Protective Actions in Complex with Polymeric Carrier on General Toxicity of Doxorubicin In Vivo

This study reports a dose-dependent pro-apoptotic action of synthetic cannabimimetic N-stearoylethanolamine (NSE) on diverse cancer cell lines, including multidrug-resistant models. No antioxidant or cytoprotective effects of NSE were found when it was applied together with doxorubicin. A complex of...

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Detalles Bibliográficos
Autores principales: Panchuk, Rostyslav, Skorokhyd, Nadiya, Chumak, Vira, Lehka, Lilya, Kosiakova, Halyna, Horid’ko, Tetyana, Hudz, Iehor, Hula, Nadiya, Riabtseva, Anna, Mitina, Nataliya, Zaichenko, Alexander, Heffeter, Petra, Berger, Walter, Stoika, Rostyslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055797/
https://www.ncbi.nlm.nih.gov/pubmed/36986696
http://dx.doi.org/10.3390/pharmaceutics15030835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055797/
https://www.ncbi.nlm.nih.gov/pubmed/36986696
http://dx.doi.org/10.3390/pharmaceutics15030835

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