Molecular Mechanisms Underlying TNFα-Induced Mitochondrial Biogenesis in Human Airway Smooth Muscle

Proinflammatory cytokines such as TNFα mediate airway inflammation. Previously, we showed that TNFα increases mitochondrial biogenesis in human ASM (hASM) cells, which is associated with increased PGC1α expression. We hypothesized that TNFα induces CREB and ATF1 phosphorylation (pCREB(S133) and pATF...

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Detalles Bibliográficos
Autores principales: Dasgupta, Debanjali, Mahadev Bhat, Sanjana, Price, Alexis L., Delmotte, Philippe, Sieck, Gary C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055892/
https://www.ncbi.nlm.nih.gov/pubmed/36982859
http://dx.doi.org/10.3390/ijms24065788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055892/
https://www.ncbi.nlm.nih.gov/pubmed/36982859
http://dx.doi.org/10.3390/ijms24065788

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