Heparan sulfate glycomimetics via iterative assembly of “clickable” disaccharides

Heparan sulfate (HS) glycosaminoglycans are widely expressed on the mammalian cell surfaces and extracellular matrices and play important roles in a variety of cell functions. Studies on the structure–activity relationships of HS have long been hampered by the challenges in obtaining chemically defi...

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Detalles Bibliográficos
Autores principales: Yang, Cangjie, Deng, Yu, Wang, Yang, Xia, Chaoshuang, Mehta, Akul Y., Baker, Kelly J., Samal, Anuj, Booneimsri, Putthipong, Lertmaneedang, Chanthakarn, Hwang, Seung, Flynn, James P., Cao, Muqing, Liu, Chao, Zhu, Alec C., Cummings, Richard D., Lin, Cheng, Mohanty, Udayan, Niu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055906/
https://www.ncbi.nlm.nih.gov/pubmed/37006675
http://dx.doi.org/10.1039/d3sc00260h

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