Identification of Z-Tyr-Ala-CHN(2), a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2

The ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is partly under control by vaccination. However, highly potent and safe antiviral drugs for SARS-CoV-2 are still needed to avoid development of severe COVID-19. We report the discovery of a small m...

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Detalles Bibliográficos
Autores principales: Doijen, Jordi, Temmerman, Koen, Van den Eynde, Christel, Diels, Annick, Van den Broeck, Nick, Van Gool, Michiel, Heo, Inha, Jaensch, Steffen, Zwaagstra, Marleen, Diosa Toro, Mayra, Chiu, Winston, De Jonghe, Steven, Leyssen, Pieter, Bojkova, Denisa, Ciesek, Sandra, Cinatl, Jindrich, Verschueren, Lore, Buyck, Christophe, Van Kuppeveld, Frank, Neyts, Johan, Van Loock, Marnix, Van Damme, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10055926/
https://www.ncbi.nlm.nih.gov/pubmed/36985290
http://dx.doi.org/10.3390/microorganisms11030717

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